Distal Weakness: Difference between revisions

Latest revision as of 19:36, 11 March 2023

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Muscle weakness can be categorised into various patterns to assist with the differential diagnosis. Reduced grip strength, weakness in wrist flexion or extension, diminished plantar flexion strength, and foot drop are common features of distal weakness. Patients with this pattern struggle to walk on their heels or toes. Foot drop can be identified by resisting the patient's attempt to dorsiflex the ankle.

Classification

Distal Weakness

Myopathic

Non-Myopathic

Acquired

Genetic

Inclusion body myositis

Myotonic dystrophy type 1
Distal myopathies: Welander, Udd, Markesbery-Griggs, Nonaka, Laing, Miyoshi

Nerve: Most neuropathies
Motor Neuron: motor neuron disease in early stage
Neuromuscular Junction: rare presentations of myaesthenia gravis

References

Literature Review

Reviews from the last 7 years: review articles, free review articles, systematic reviews, meta-analyses, NCBI Bookshelf

Articles from all years: PubMed search, Google Scholar search.

TRIP Database: clinical publications about evidence-based medicine.

Other Wikis: Radiopaedia, Wikipedia Search, Wikipedia I Feel Lucky, Orthobullets,

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 {{family tree | | C01 | | C02 | | | | |!| | | |C01=Acquired|C02=Genetic}}
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-{{family tree | | D01 | | D02 | | | | D03 | | |D01=<ul><li>[[Myositis#Inclusion_Body_Myositis|Inclusion body myositis]]</li></ul>|D02=<ul><li>[[Myotonic Dystrophy|Myotonic dystrophy type 1]]</li><li>Distal myopathies: Welander, Udd, Markesbery-Griggs, Nonaka, Laing, Miyoshi</li></ul>|D03=<ul><li><strong>Nerve: </strong>Most neuropathies</li><li><strong>Motor Neuron: </strong> motor neuron disease in early stage</li><li><strong>Neuromuscular Junction:</strong> rare presentations of myaesthenia gravis</li></ul>}}
+{{family tree | | D01 | | D02 | | | | D03 | | |D01=<ul><li>[[Myositis#Inclusion_Body_Myositis|Inclusion body myositis]]</li></ul>|D02=<ul><li>[[Myotonic Dystrophy|Myotonic dystrophy type 1]]</li><li><strong>Distal myopathies</strong>: Welander, Udd, Markesbery-Griggs, Nonaka, Laing, Miyoshi</li></ul>|D03=<ul><li><strong>Nerve: </strong>Most neuropathies</li><li><strong>Motor Neuron: </strong> motor neuron disease in early stage</li><li><strong>Neuromuscular Junction:</strong> rare presentations of myaesthenia gravis</li></ul>}}
 {{family tree/end}}