File:Costameres.jpg

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Summary

Cellular location of costameres in striated muscle. Shown in A is a schematic diagram illustrating costameres as circumferential elements that physically couple peripheral myofibrils to the sarcolemma in periodic register with the Z-disk. The protein composition of costameres is shown in expanded form in Fig. 2. Shown in B is an inside-out sarcolemma that was mechanically peeled from a single myofibre and stained with antibodies to ฮณ-actin to reveal the costameric cytoskeleton. Bar, 10 ฮผm. B is reproduced from Ref. 17 by copyright permission of The Rockefeller University Press

From Ervasti JM. Costameres: the Achilles' heel of Herculean muscle. J Biol Chem. 2003 Apr 18;278(16):13591-4. doi: 10.1074/jbc.R200021200. Epub 2003 Jan 29. PMID: 12556452.

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current15:29, 10 August 2021Thumbnail for version as of 15:29, 10 August 2021363 ร— 482 (76 KB)Jeremy (talk | contribs)From Ervasti JM. Costameres: the Achilles' heel of Herculean muscle. J Biol Chem. 2003 Apr 18;278(16):13591-4. doi: 10.1074/jbc.R200021200. Epub 2003 Jan 29. PMID: 12556452.

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