EBQ:Twin Spine Study: Difference between revisions

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==Design==
==Design==
The Twin Spine Study, which started in 1991, is a multidisciplinary, multinational research project with collaborators primarily in Canada, Finland, and the United States. They investigated occupational exposures, driving and whole-body vibration exposure, smoking exposure, anthropomorphic factors, heritability, and the identification of genotypes associated with disc degeneration.
==Population Studied==
==Population Studied==
===Inclusion Criteria===
===Inclusion Criteria===

Revision as of 07:27, 24 June 2020

Battie M, et al. "The Twin Spine Study: Contributions to a changing view of disc degeneration". The Spine Journal. 2009. 9:47-59.
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Clinical Question

What is the contribution of genetics to disc degeneration?

Conclusion

There is a substantial influence of heredity on lumbar disc degeneration. There is little effect on disc degeneration from occupational and leisuretime physical loading, and increased loading may have a small benefit. There is only a small effect from smoking. Body weight and muscle strength have modest effects on disc degeneration.

Design

The Twin Spine Study, which started in 1991, is a multidisciplinary, multinational research project with collaborators primarily in Canada, Finland, and the United States. They investigated occupational exposures, driving and whole-body vibration exposure, smoking exposure, anthropomorphic factors, heritability, and the identification of genotypes associated with disc degeneration.

Population Studied

Inclusion Criteria

Exclusion Criteria

Baseline Characteristics

Interventions

Outcomes/Results

Primary Outcomes

Secondary Outcomes

Adverse events

Discussion

Criticism

Funding

See Also