WikiMSK:Updates

Latest RCTs

Impact of Intermittent Theta Burst Stimulation on Pain Relief and Brain Connectivity in Chronic Low Back Pain: CONCLUSION: iTBS may alleviate pain in CLBP patients by enhancing DLPFC connectivity with the cerebellum and occipital gyrus.; Chuhuai Wang. European journal of pain (London, England). 2025-05-05 00:00:00
HOPE for Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorder (HSD)-A Pilot Randomised Controlled Trial of Feasibility, Acceptability and Appropriateness: CONCLUSION: The HOPE program seemed feasible, acceptable and appropriate, with preliminary improvements in worst pain intensity and impact of hypermobility. Our findings warrant a fully powered tri...; Cliffton Chan. European journal of pain (London, England). 2025-04-29 00:00:00
Manual therapy and neck-specific exercise are equally effective for treating non-specific neck pain but only when exercise adherence is maximised: A randomised controlled trial: CONCLUSION: A four-week intervention of manual therapy was more effective than exercise, however when exercise adherence was ≥95 %, the interventions were equally effective. Manual therapy may on...; Ion Lascurain-Aguirrebeña. Musculoskeletal science & practice. 2025-04-24 00:00:00
The Effect of Information on the Time Course of Pain During an Episode of Acute Experimentally Induced Low Back Pain-A Randomised Experiment: CONCLUSIONS: We simulated an episode of low back pain and found that information based on tissue sensitivity and advice to remain active did not improve pain compared to information referencing tis...; T Skuli Palsson. European journal of pain (London, England). 2025-04-20 00:00:00
Stair climb muscle power is associated with gait speed, sit-to-stand performance, patient-reported outcomes and objective measures of mechanical muscle function in individuals with knee osteoarthri...: CONCLUSIONS: SCT power correlates positively with functional performance, PROMs and mechanical lower limb muscle function in male and female individuals with knee-OA.; S Peter Magnusson. Musculoskeletal science & practice. 2025-04-18 00:00:00
Cryo-Induced Hypoalgesia: The Effects of an Acute Cryochamber Exposure on Pain Perception-A Randomised Controlled Cross-Over Trial: CONCLUSIONS: This study demonstrates that a three-minute cryochamber exposure induces robust hypoalgesia in healthy participants, as indicated by increased PPT, lasting up to 30 min but gradually d...; Thomas Hilberg. European journal of pain (London, England). 2025-04-05 00:00:00
Greater Occipital Nerve Block at Two Levels Spares the Need for an Epidural Blood Patch for Managing Postdural Puncture Headache: A Randomized Comparative Trial: CONCLUSION: Bilevel GONB provided was superior to single level blocks and intramuscular injection with no 24 hour postprocedure failure, a low recurrence rate, and totally negated the need for an e...; Samar A Salman. Pain physician. 2025-04-01 00:00:00
Evaluation of Genicular Nerve Blocks Durations With and Without Corticosteroid: A Single-blind, Randomized Controlled Trial: CONCLUSION: The addition of a corticosteroid to local anesthetic for GNB may prolong initial analgesic effects within the first postprocedure 24 hours. However, there is no analgesic difference in ...; Chong H Kim. Pain physician. 2025-04-01 00:00:00
Ultrasound-Guided Stellate Ganglion Block for the Treatment of Chronic Migraine in Adults: Study Protocol for a Randomized, Open-Label, Blinded Endpoint Trial: CONCLUSIONS: This study is a randomized controlled trial with a relatively large sample size to demonstrate the potential benefits of combined SGBs and drug therapy for CM patients. In the short te...; Fang Luo. Pain physician. 2025-04-01 00:00:00
The influence of education on pain during and following acute exercise in people with knee osteoarthritis: A randomised controlled trial: CONCLUSION: A single exercise session reduces pain in people with knee OA, but this was not influenced by pre-exercise education about EIH. Further research is needed to understand if and how EIH c...; Matthew D Jones. Musculoskeletal science & practice. 2025-03-26 00:00:00
Beliefs and experiences of individuals with patellar tendinopathy following a rehabilitation program: A nested qualitative study: CONCLUSIONS: The findings suggest that individuals with PT are primarily motivated by the hope of improving symptoms and function, as well as the condition's substantial impact on their ability to ...; Peter Malliaras. Musculoskeletal science & practice. 2025-03-18 00:00:00
Biplane Ultrasound Versus Fluoroscopy for Guidance of Percutaneous Lumbar Intervertebral Foramen Insertion : A Randomized Controlled Clinical Trial: CONCLUSION: Biplane US provides an accurate, safe, and convenient approach for PLIFI. With further clinical practice, biplane US would be conducive to rapid skill acquisition for novices and has th...; Mingbo Zhang. Spine. 2025-03-17 00:00:00
Cost-Effectiveness of Instrumented Versus Uninstrumented Posterolateral Fusion for Single-Level Degenerative Spondylolisthesis: CONCLUSION: Instrumented fusion is cost-effective compared uninstrumented fusion, with an incremental cost-effectiveness ration well below the standard range of cost-effectivenes, the difference in...; Jan Sørensen. Spine. 2025-02-20 00:00:00
Minimal important change in the Hip Disability and Osteoarthritis Outcome Score and the European Quality of Life 5 Dimensions in adults with hip osteoarthritis after 12 weeks of exercise: CONCLUSIONS: The reported MIC values indicate the minimal improvement that the average patient with hip OA would consider important after 12 weeks of exercise and will help clinicians and researche...; Troels Kjeldsen. Musculoskeletal science & practice. 2025-02-19 00:00:00
Ten Minutes of Core Stabilisation Exercise Result in Local Exercise-Induced Hypoalgesia in Patients With Chronic Unspecific Low Back Pain: CONCLUSION: A 10-min isometric core stabilisation exercise results in local lumbar EIH, while no systemic effects are observed. A higher degree of catastrophizing is associated with lower hypoalges...; Thomas Hilberg. European journal of pain (London, England). 2025-02-09 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. RCTs from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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Latest Systematic Reviews

Computed tomography versus magnetic resonance imaging of the cervical spine in the spinal clearance of trauma patients: a systematic review and meta-analyses: CONCLUSION: Trauma patients with a negative CT cervical spine had a 17% chance of missed injuries if MRI cervical spine was not performed, with paediatric and alert patients having a higher risk. T...; Hwee Weng Dennis Hey. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-05-23 00:00:00
Effectiveness and reporting quality of blood flow restriction training in the rehabilitation of patients with upper limb musculoskeletal disorders: A systematic review: CONCLUSIONS: This systematic review identified limited and low-quality evidence that BFRT is effective in the physical rehabilitation of patients with upper limb musculoskeletal disorders. Addition...; Filip Struyf. PM & R : the journal of injury, function, and rehabilitation. 2025-05-23 00:00:00
Family-Related Factors in Children and Adolescents With Chronic Pain: A Systematic Review: CONCLUSIONS: Most of the studies were cross-sectional with a moderate or high risk of bias, reporting on the parenting individual-, dyadic-, and contextual-related factors. In the included studies,...; Jordi Miró. European journal of pain (London, England). 2025-05-23 00:00:00
Normative Thoracic, Lumbar, Pelvic and Global Sagittal Alignment Parameters for Asymptomatic Adults: A Systematic Review and Meta-Analysis of >35,900 Volunteers: CONCLUSION: LL-S1, PI and PT were all higher in women. Regional TK, PT, PI-LL, SVA, TPA all increased with age, while LL-S1 and SSA decreased. Global TK, regional TK, LL-S1, PI, and PI-LL all had s...; Zeeshan M Sardar. Spine. 2025-05-23 00:00:00
ALIF vs. posterior fusion for lumbar degenerative disease: comparable efficacy but elevated risk of severe complications-a systematic review and meta-analysis: CONCLUSION: Clinical outcomes measured by VAS and ODI were comparable between anterior and posterior approaches, demonstrating similar efficacy in treating lumbar degenerative diseases. However, th...; Vladimir Tonello de Vasconcelos. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-05-22 00:00:00
The Impact of Tai Chi on Physical and Mental Well-being in Individuals with Knee Osteoarthritis: A Systematic Review and Meta-analysis: CONCLUSION: The results of this study suggest that Tai Chi may have a significant effect on reducing pain, joint stiffness, and improving physical function in individuals with knee osteoarthritis, ...; Ming Zhou. American journal of physical medicine & rehabilitation. 2025-05-21 00:00:00
Effects of electrical and magnetic stimulation on upper extremity function after stroke: A systematic review and network meta-analysis: CONCLUSIONS: NMES plus rPMS might be the best intervention to improve upper extremity functions, with NMES plus TMS most likely to lead to improved ADL but the quality of the evidence is low.; Ammarin Thakkinstian. PM & R : the journal of injury, function, and rehabilitation. 2025-05-21 00:00:00
Adverse Impact of Diabetes on Spine Fusion and Patient-Reported Outcomes: A Systematic Review and Meta-Analysis: CONCLUSION: Patients with diabetes who underwent spinal surgery had a higher incidence of pseudoarthrosis and worse functional outcomes compared to non-diabetic patients. These findings underscore ...; Rick C Sasso. Spine. 2025-05-19 00:00:00
Letter to the editor concerning "impact of erector spinae plane block on postoperative recovery quality in spinal surgery: a systematic review and meta-analysis" by Zhang L, et al. (Eur spine J. 20...: No abstract; Lijiang Lv. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-05-17 00:00:00
Exercise improves stair climbing performance after stroke: A systematic review of randomized trials with meta-analysis: CONCLUSION: This systematic review provided very-low-quality evidence that 6 weeks of planned, structured, and repetitive exercises, performed during 50 minutes, four times per week, improve stair ...; Stella Maris Michaelsen. PM & R : the journal of injury, function, and rehabilitation. 2025-05-13 00:00:00
Accuracy and Safety Assessment of Subaxial Cervical Pedicle Screw Instrumentation: A Systematic Review: CONCLUSION: Our comprehensive review of more than 14,000 subaxial CPSs inserted found rates of high 84% overall accuracy and low 1.2% perioperative complications (i.e., attributed to a misplaced sc...; Edin Nevzati. The spine journal : official journal of the North American Spine Society. 2025-05-07 00:00:00
Basilar Invagination Diagnosis, Classification, and Radiology: WFNS Spine Committee Recommendations: CONCLUSIONS: Diagnosis of basilar invagination should be made by midsagittal craniocervical x-rays, CTs or MRI. There are two types of basilar invagination: type I basilar invagination is associate...; Oscar L Alves. Spine. 2025-05-07 00:00:00
Can quantitative sensory testing predict treatment outcomes in hip and knee osteoarthritis? A systematic review and meta-analysis of individual participant data: An individual participant data (IPD) meta-analysis can assess the predictive value of data on outcomes at the individual level, offering a potential tool for developing personalized pain management...; Kristian Kjær-Staal Petersen. Pain. 2025-05-01 00:00:00
Effectiveness of Lee Silverman Voice Treatment (LSVT®BIG) for improving motor function in patients with Parkinson's disease: a systematic review and meta-analysis of randomised clinical trials: CONCLUSIONS: LSVT®BIG could be more effective than general exercise in improving gait speed and motor function in patients with mild to moderate Parkinson's disease. However, due to the variabilit...; Henry Mauricio Parada-Gereda. American journal of physical medicine & rehabilitation. 2025-04-29 00:00:00
Prevalence and characteristics of persistent pain among head and neck cancer survivors: A systematic review and meta-analysis: CONCLUSION: This systematic review highlights that almost third of head and neck cancer survivors are under persistent pain after finishing cancer treatment. No final conclusions can be drawn as to...; Carolina Fernández-Lao. Pain medicine (Malden, Mass.). 2025-04-28 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. Reviews from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

Pubmed Link