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Latest RCTs [1]

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Integrated Meditation and Exercise Therapy: A Randomized Controlled Pilot of a Combined Nonpharmacological Intervention Focused on Reducing Disability and Pain in Patients with Chronic Low Back Pain
CONCLUSION: . Overall, 4 weeks of MedExT produced suggestive between-group trends for disability, significant between-group differences for measures of pain, and significant within-group increases...
Benedict J Kolber. Pain medicine (Malden, Mass.). 2021-02-23 00:00:00
Effect of Pain Education, Cryotherapy, and Transcutaneous Electrical Nerve Stimulation on the Pain, Functional Capacity, and Quality of Life in Patients With Nonspecific Chronic Low Back Pain: A Si...
CONCLUSIONS: This study showed that with pain education, there was no difference between cryotherapy and transcutaneous electrical nerve stimulation alone, combined, or placebo mode in improving pa...
Wouber Herickson de Brito Vieira. American journal of physical medicine & rehabilitation. 2021-02-17 00:00:00
Benefits of Adding Gluteal Dry Needling to a Four-Week Physical Exercise Program in a Chronic Low Back Pain Population. A Randomized Clinical Trial
CONCLUSIONS: In chronic low back patients, adding dry needling to a four-week exercise program has an additional benefit in pain and sensitivity compared with adding sham dry needling to the same e...
Daniel Pecos-Martín. Pain medicine (Malden, Mass.). 2021-02-13 00:00:00
Effect of Drug Disposal Kits and Fact Sheets on Elimination of Leftover Prescription Opioids: The DISPOSE Multi-Arm Randomized Controlled Trial
CONCLUSIONS: These findings suggest that passive provision of a drug disposal kit at prescription pickup did not increase rates of leftover opioid disposal when compared with provision of a fact sh...
Constance L Monitto. Pain medicine (Malden, Mass.). 2021-02-12 00:00:00
Short-Term Effect of Scalp Acupuncture on Pain, Sleep Disorders, and Quality of Life in Patients with Temporomandibular Disorders: A A Randomized Clinical Trial
CONCLUSIONS: The scalp acupuncture proved to be another alternative for pain relief in patients with TMD, demonstrating positive results in the short term. However, it was not as effective in impro...
Gustavo Augusto Seabra Barbosa. Pain medicine (Malden, Mass.). 2021-02-09 00:00:00
Efficacy and Long-term Effect of Radiofrequency Denervation in Patients with Clinically Diagnosed Cervical Facet Joint Pain: A Double-blind Randomized Controlled Trial
CONCLUSIONS: We did not observe significant differences between RF denervation combined with injection of local anesthesia compared with local anesthesia only at 6 months follow-up. We found a diff...
Sander M J van Kuijk. Spine. 2021-02-03 00:00:00
Effectiveness of a structured group intervention based on pain neuroscience education for patients with fibromyalgia in primary care: A multicentre randomized open-label controlled trial
CONCLUSIONS: In this sample of patients with FM, the improvement in quality of life and control of symptoms obtained by adding a PNE intervention showed promising results, equalling or surpassing p...
FIMIDOC Working Group researchers. European journal of pain (London, England). 2021-01-29 00:00:00
Mindful Self-Compassion program for chronic pain patients: A randomized controlled trial
CONCLUSIONS: Mindful Self-Compassion is an appropriate therapeutic approach for CP patients and may result in greater benefits on self-compassion and emotional well-being than CBT.
Ángela Palao-Tarrero. European journal of pain (London, England). 2021-01-20 00:00:00
Internet-delivered acceptance and commitment therapy as microlearning for chronic pain: A randomized controlled trial with 1-year follow-up
CONCLUSIONS: Internet-ACT as microlearning may improve a broad range of outcomes in chronic pain.
Rikard K Wicksell. European journal of pain (London, England). 2021-01-18 00:00:00
Brief preoperative mind-body therapies for total joint arthroplasty patients: a randomized controlled trial
Although knee and hip replacements are intended to relieve pain and improve function, up to 44% of knee replacement patients and 27% of hip replacement patients report persistent postoperative join...
Eric L Garland. Pain. 2021-01-15 00:00:00
Photobiomodulation therapy is not better than placebo in patients with chronic nonspecific low back pain: a randomised placebo-controlled trial
Photobiomodulation therapy (PBMT) has been used in several musculoskeletal disorders to reduce pain, inflammation, and promoting tissue regeneration. The current evidence about the effects of PBMT...
Shaiane Silva Tomazoni. Pain. 2021-01-15 00:00:00
Effect of anodal high-definition transcranial direct current stimulation on the pain sensitivity in a healthy population: a double-blind, sham-controlled study
High-definition transcranial direct current stimulation (HD-tDCS) of brain areas related to pain processing may provide analgesic effects evident in the sensory detection and pain thresholds. The s...
Thomas Graven-Nielsen. Pain. 2021-01-15 00:00:00
Conditioned open-label placebo for opioid reduction after spine surgery: a randomized controlled trial
Placebo effects have traditionally involved concealment or deception. However, recent evidence suggests that placebo effects can also be elicited when prescribed transparently as "open-label p...
Kristin L Schreiber. Pain. 2021-01-15 00:00:00
Ultrasound-guided transversus abdominis plane block vs trigger point injections for chronic abdominal wall pain: a randomized clinical trial
The primary aim of this randomized clinical trial is to investigate the effects of ultrasound-guided transversus abdominis plane (TAP) vs ultrasound-guided trigger point injections (TPIs) on numeri...
W Michael Hooten. Pain. 2021-01-12 00:00:00
Predictive Factors Affecting Surgical Outcomes in Patients with Degenerative Lumbar Spondylolisthesis
CONCLUSION: While the degree of vertebral slippage and the presence of angulation were not associated with poor recovery after surgery for lumbar degenerative spondylolisthesis, postoperative outco...
Atsushi Okawa. Spine. 2021-01-11 00:00:00


RCTs from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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Latest Systematic Reviews [2]

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Early Predictors of Neurological Outcomes After Traumatic Spinal Cord Injury: A Systematic Review and Proposal of a Conceptual Framework
CONCLUSIONS: This study provides a comprehensive review of predictors of neurological outcomes after traumatic spinal cord injury. It also highlights the heterogeneity of outcomes used by studies t...
Jean-Marc Mac-Thiong. American journal of physical medicine & rehabilitation. 2021-06-16 00:00:00
Perioperative factors associated with persistent post-surgical pain after hysterectomy, cesarean section, prostatectomy, and donor nephrectomy: a systematic review and meta-analysis
Persistent postsurgical pain (PPSP) is a common, and often disabling postoperative morbidity, but many questions remain about factors associated with PPSP. This systematic review and meta-analysis...
Simon Haroutounian. Pain. 2021-06-14 00:00:00
The Relationship of Aging and Smoking with Rotator Cuff Disease: A Systematic Review and Meta-Analysis
CONCLUSION: In this systematic review and meta-analysis, increasing age was a strong risk factor for rotator cuff disease. The finding that current smokers are more likely to have rotator cuff dise...
Nitin B Jain. American journal of physical medicine & rehabilitation. 2021-06-14 00:00:00
Changes in kinematics, kinetics, and muscle activity in patients with lumbar spinal stenosis during gait: systematic review
CONCLUSION: Although numerous studies have investigated gait function in patients with LSS, gait alterations in joint kinetics and muscle activity over time remain largely unknown. In addition, the...
Erin M Mannen. The spine journal : official journal of the North American Spine Society. 2021-06-11 00:00:00
Which traumatic spinal injury creates which degree of instability? A systematic quantitative review
CONCLUSIONS: Specific traumatic spinal injuries produce characteristic but complex three-dimensional degrees of instability, which depend on the type, level, and morphology of the injury. Future st...
Hans-Joachim Wilke. The spine journal : official journal of the North American Spine Society. 2021-06-11 00:00:00
Dry Needling versus Trigger Point Injection for Neck Pain Symptoms Associated with Myofascial Trigger Points: A Systematic Review and Meta-analysis
CONCLUSION: Low evidence suggests a superior effect of TrP injection (wet needling) for decreasing pain of cervical muscle TrPs at short-term as compared to dry needling. No significant effects on...
Gustavo Plaza-Manzano. Pain medicine (Malden, Mass.). 2021-06-11 00:00:00
The association between pain scores and disc height change following discectomy surgery in lumbar disc herniation patients: a systematic review and meta-analysis
CONCLUSION: Discectomy surgery produces significant and quantifiable reductions in DH and DHI. Additionally, the reduction in DH is responsible for the decrease in back pain scores post discectomy,...
Ashish D Diwan. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-06-11 00:00:00
Evaluation of open and minimally invasive spinal surgery for the treatment of thoracolumbar metastatic epidural spinal cord compression: a systematic review
CONCLUSION: MESCC carries significant morbidity and mortality. Surgical approaches for palliative treatment should account for this fact. We conclude that MIS techniques offer a viable alternative...
Bruce Frankel. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-05-30 00:00:00
Mathematical and computational models for pain: a systematic review
CONCLUSIONS: Although understudied, the development of mathematical models may augment the current understanding of pain by providing directions for testable hypotheses of its underlying mechanisms...
Max Ortiz-Catalan. Pain medicine (Malden, Mass.). 2021-05-29 00:00:00
Placebo effects in low back pain; a systematic review and meta-analysis of the literature
CONCLUSIONS: This review shows a significant contribution of placebo effects to chronic LBP symptom relief in clinical and experimental conditions. The meta-analysis revealed that placebo effects c...
K M Szadek. European journal of pain (London, England). 2021-05-29 00:00:00
Management of spinal aneurysms associated with arteriovenous malformations: systematic literature review and illustrative case
CONCLUSIONS: The treatment strategy for AVM-associated spinal aneurysms should be tailored on the single patient. In presence of large aneurysms that cause mass-effect symptoms, when rupture of the...
Pietro Fiaschi. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-05-27 00:00:00
Perioperative outcomes following preoperative epidural analgesia in hip fracture patients undergoing surgical repair: A systematic review
CONCLUSIONS: Preoperative epidural analgesia for hip fracture may reduce perioperative cardiac events and mortality, but the number of included studies in this systematic review was low. More resea...
Susan M Lee. Pain medicine (Malden, Mass.). 2021-05-22 00:00:00
The association between vertebral endplate structural defects and back pain: a systematic review and meta-analysis
CONCLUSION: Overall, there is moderate quality evidence of an association between back pain and endplate structural defects, which is most evident for erosion, sclerosis and Schmorl's nodes. Go...
Michele C Battié. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-05-22 00:00:00
The role of TaqI, ApaI and BsmI polymorphisms of VDR gene in lumbar spine pathologies: systematic review and meta-analysis
CONCLUSIONS: Our findings indicate that TaqI and ApaI polymorphisms of the VDR gene are important risk factors for developing lumbar spine pathologies. Moreover, the TaqI polymorphism is a risk fac...
Nonanzit Pérez-Hernández. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-05-22 00:00:00
A Systematic Review of Practiced-Based Research of Complementary and Integrative Health Therapies as Provided for Pain Management in Clinical Settings: Recommendations for the Future and A Call to...
CONCLUSIONS: Findings from this systematic review of practice-based, real-word research indicate that CIH therapies exert positive effects on various pain outcomes. Although all studies reported be...
Jeffery A Dusek. Pain medicine (Malden, Mass.). 2021-05-19 00:00:00


Reviews from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

View more articles