WikiMSK:Updates

Latest RCTs

Cryo-Induced Hypoalgesia: The Effects of an Acute Cryochamber Exposure on Pain Perception-A Randomised Controlled Cross-Over Trial: CONCLUSIONS: This study demonstrates that a three-minute cryochamber exposure induces robust hypoalgesia in healthy participants, as indicated by increased PPT, lasting up to 30 min but gradually d...; Thomas Hilberg. European journal of pain (London, England). 2025-04-05 00:00:00
Greater Occipital Nerve Block at Two Levels Spares the Need for an Epidural Blood Patch for Managing Postdural Puncture Headache: A Randomized Comparative Trial: CONCLUSION: Bilevel GONB provided was superior to single level blocks and intramuscular injection with no 24 hour postprocedure failure, a low recurrence rate, and totally negated the need for an e...; Samar A Salman. Pain physician. 2025-04-01 00:00:00
Evaluation of Genicular Nerve Blocks Durations With and Without Corticosteroid: A Single-blind, Randomized Controlled Trial: CONCLUSION: The addition of a corticosteroid to local anesthetic for GNB may prolong initial analgesic effects within the first postprocedure 24 hours. However, there is no analgesic difference in ...; Chong H Kim. Pain physician. 2025-04-01 00:00:00
Ultrasound-Guided Stellate Ganglion Block for the Treatment of Chronic Migraine in Adults: Study Protocol for a Randomized, Open-Label, Blinded Endpoint Trial: CONCLUSIONS: This study is a randomized controlled trial with a relatively large sample size to demonstrate the potential benefits of combined SGBs and drug therapy for CM patients. In the short te...; Fang Luo. Pain physician. 2025-04-01 00:00:00
Cost-Effectiveness of Instrumented Versus Uninstrumented Posterolateral Fusion for Single-Level Degenerative Spondylolisthesis: CONCLUSION: Instrumented fusion is cost-effective compared uninstrumented fusion, with an incremental cost-effectiveness ration well below the standard range of cost-effectivenes, the difference in...; Jan Sørensen. Spine. 2025-02-20 00:00:00
Minimal important change in the Hip Disability and Osteoarthritis Outcome Score and the European Quality of Life 5 Dimensions in adults with hip osteoarthritis after 12 weeks of exercise: CONCLUSIONS: The reported MIC values indicate the minimal improvement that the average patient with hip OA would consider important after 12 weeks of exercise and will help clinicians and researche...; Troels Kjeldsen. Musculoskeletal science & practice. 2025-02-19 00:00:00
Ten Minutes of Core Stabilisation Exercise Result in Local Exercise-Induced Hypoalgesia in Patients With Chronic Unspecific Low Back Pain: CONCLUSION: A 10-min isometric core stabilisation exercise results in local lumbar EIH, while no systemic effects are observed. A higher degree of catastrophizing is associated with lower hypoalges...; Thomas Hilberg. European journal of pain (London, England). 2025-02-09 00:00:00
Comparing the efficacy of two E-learning programs on physiotherapists' knowledge, attitudes, and confidence in musculoskeletal pain management: A randomized trial: CONCLUSION: Both e-learning programs effectively enhanced physiotherapists' knowledge, attitudes, and confidence in musculoskeletal pain management, demonstrating the value of e-learning for contin...; Felipe J J Reis. Musculoskeletal science & practice. 2025-02-06 00:00:00
Clinical Trial of Ozonated Water Enema for the Treatment of Fibromyalgia: A Randomized, Double-Blind Trial: CONCLUSION: This trial confirmed that the symptoms of pain, anxiety, and sleep disorders in FM patients were effectively relieved after treatment with an ozonated water enema. Furthermore, the ozon...; Lijun Liao. Pain physician. 2025-02-04 00:00:00
Rhomboid Intercostal versus Serratus Anterior Plane Block for Analgesia After Thoracodorsal Artery Perforator Flap Following Partial Mastectomy: A Randomized Controlled Trial: CONCLUSION: Because of its ability to block both the anterior and posterior hemithorax, the RIB, is more efficient than the SAB at controlling acute pain and reducing opioid consumption in patients...; Heba M Fathi. Pain physician. 2025-02-04 00:00:00
Adjuvants to Conventional Management of Postdural Puncture Headache Following Obstetric Surgery Under Spinal Anesthesia: Mirtazapine vs. Sumatriptan: CONCLUSIONS: Adding either mirtazapine or sumatriptan to the CM of PDPH following obstetric SA was associated with lower means of headache intensities, higher rates of complete response to medical ...; Ahmad Mahmoud Hasseb. Pain physician. 2025-02-04 00:00:00
A Placebo-Controlled Randomized Trial Comparing Oral Midazolam, Dexmedetomidine, and Gabapentin on Prophylaxis of Emergence Agitation After Sevoflurane Anesthesia in Adenotonsillectomy: CONCLUSION: Premedication using oral midazolam, DEX, or gabapentin reduced the incidence of EA, and DEX provided the best sedation and hemodynamics of all.; Amir Abouzkry Elsayed. Pain physician. 2025-02-04 00:00:00
Fluoroscopy-guided Intradiscal Radiopaque Gelified Ethanol Injection Using an Anteroposterior View Compared to an Oblique View: A Randomized Controlled Trial: CONCLUSION: An anteroposterior view radiopaque gelified ethanol injection is a promising alternative to the conventional oblique view technique for radicular leg pain management. This novel approac...; Sogol Asgari. Pain physician. 2025-02-04 00:00:00
Combining procedural and behavioral treatments for chronic low back pain: A pilot feasibility randomized controlled trial: CONCLUSION: We conclude that it is feasible to conduct a randomized controlled trial combining procedural and behavioral treatments for CLBP.; Pradeep Suri. PM & R : the journal of injury, function, and rehabilitation. 2025-02-04 00:00:00
The effects of microprocessor prosthetic knee use in early rehabilitation: A pilot randomized controlled trial: CONCLUSIONS: Enrollment goals were limited by the COVID-19 pandemic, but all 15 participants who received a study prosthesis finished the 3-month pilot study. The MPK group generally had better 3-m...; Brian J Hafner. PM & R : the journal of injury, function, and rehabilitation. 2025-02-03 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. RCTs from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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Latest Systematic Reviews

A systematic review and meta-analysis of pharmacological methods to manipulate experimentally induced secondary hypersensitivity: Understanding the physiology of specific clinical features of persistent pain, such as secondary hypersensitivity, is crucial for developing effective treatments. This systematic review and meta-an...; Victoria J Madden. Pain. 2025-04-14 00:00:00
The effectiveness of physiotherapy and rehabilitation after cervical spinal surgery: a systematic review: CONCLUSION: In all the studies, there were drawbacks such as uncertainty of compliance with the physiotherapy (PT) program and controversial appropriateness. As these studies had a high risk of bia...; Ozlem Ulger. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-04-11 00:00:00
Deviation from preoperative planning and pedicle screw accuracy in navigated and robotic spinal fusion: a systematic review: CONCLUSION: Although preoperative planning allows the surgeon to plan the final position of the screw most appropriately, mild deviations from it do not seem to excessively influence the accuracy o...; Vincenzo Denaro. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-04-08 00:00:00
Virtual Reality-Assisted Rehabilitation for Patients Undergoing Total Knee Arthroplasty: A Systematic Review and Meta-Analysis: CONCLUSIONS: VRehab effectively reduced postsurgical pain and enhanced the recovery of function, mobility, balance, and range of motion in patients undergoing TKA. Integrating VRehab into standard ...; Shin-Da Lee. American journal of physical medicine & rehabilitation. 2025-04-08 00:00:00
Differences in the clinical presentation of chronic whiplash-associated disorders and nontraumatic neck pain: a systematic review and meta-analysis: Health outcomes may be worse for individuals with whiplash-associated disorders (WAD) compared to nontraumatic neck pain (NTNP), and clinical characteristics may differ. This systematic review exam...; Michele Sterling. Pain. 2025-04-08 00:00:00
Carbon Fiber vs Titanium Pedicle Screws: A Systematic Review of Radiological, Biomechanical and Clinical Features: CONCLUSION: CF pedicle screws represent a viable alternative to Ti implants, providing equivalent biomechanical performance and outcomes while offering superior radiological clarity and dosimetric ...; Daniel G Tobert. Spine. 2025-04-08 00:00:00
Oral non-benzodiazepine muscle-relaxants for people with acute and chronic primary low back pain: a systematic review with meta-analysis: CONCLUSIONS: Non-benzodiazepine MR for acute LBP were associated with increased likelihood of pain relief and global efficacy compared to placebo. Combined therapy with analgesics/NSAIDs proved sup...; Marco Monticone. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-04-05 00:00:00
Pulmonary function does not improve after 10 years of posterior spinal fusion in adolescent idiopathic scoliosis: a systematic review and meta-analysis: CONCLUSIONS: This rigorous meta-analysis demonstrates that PSF does not enhance respiratory function in AIS patients in either the short- or long-term, as assessed using current static pulmonary me...; Carlos Barrios. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-04-05 00:00:00
Impact of erector spinae plane block on postoperative recovery quality in spinal surgery: a systematic review and meta-analysis: CONCLUSION: ESPB was associated with an improvement in the quality of recovery within the first 24 h postoperatively in patients undergoing spinal surgery, along with a reduction in the incidence o...; Ying Xie. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-04-02 00:00:00
Gray Matter Alterations in Medication Overuse Headache: A Voxel-Based Morphometry Meta-Analysis: CONCLUSION: Significant alterations in GM across various brain regions associated with pain processing, modulation, and reward have been observed in association with MOH. These observations contrib...; Zhengjie Li. Pain physician. 2025-04-01 00:00:00
Accuracy of Imaging in Dynamic Spondylolisthesis: Emerging Strategies and Understanding for Pain Physicians: A Systematic Review: CONCLUSION: The present investigation analyzed the current literature and determined that alternative imaging techniques could adequately diagnose the dynamic instability of the spine. Further rese...; Sayed E Wahezi. Pain physician. 2025-04-01 00:00:00
Nerve Block Efficacy and Safety for Acute Thoracic Herpes Zoster: A Systematic Review and Meta-analysis: CONCLUSION: In conclusion, nerve blocks with local anesthetics and steroids provide effective analgesia, reduce analgesic consumption, and lower PHN incidences in patients with acute thoracic herpe...; Yu-Lien Hsieh. Pain physician. 2025-04-01 00:00:00
The Efficacy of the Minimally Invasive Lumbar Decompression (MILD®) Procedure: A PRISMA-compliant Systemic Review and Meta-analysis: CONCLUSIONS: Our study suggests MILD is an effective and safe surgical technique for patients with stenosis from ligamentum flavum hypertrophy. This technique resulted in significant clinical impro...; Dajie Wang. Pain physician. 2025-04-01 00:00:00
Diagnostic accuracy of neurodynamic tests in upper-limb entrapment neuropathies: A systematic review and meta-analysis: CONCLUSION: Upper-limb neurodynamic tests show moderate sensitivity and low to moderate specificity for diagnosing upper-limb entrapment neuropathies, with diagnostic accuracy varying across condit...; Gustavo Plaza-Manzano. Musculoskeletal science & practice. 2025-03-29 00:00:00
Duraplasty in acute spinal cord injury: a systematic review: CONCLUSION: Expansile duraplasty shows promise in patients with aSCI and may be effective in enhancing patient outcomes. Current literature remains scarce and further studies need to be conducted.; Timothy F Witham. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-03-28 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. Reviews from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

Pubmed Link