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Latest RCTs [1]

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Comparing the Effects of Early Versus Late Exercise Intervention on Pain and Neurodynamic Mobility Following Unilateral Lumbar Microdiscectomy: A Pilot Study
CONCLUSION: Our study results showed that early exercise intervention after lumbar microdiscectomy is safe and may reduce the low back pain, decrease fear avoidance, and improve neurodynamic mobili...
Fahad AlKherayf. Spine. 2021-08-26 00:00:00
Executive Function Moderates Functional Outcomes of Engagement Strategies During Rehabilitation in Older Adults
CONCLUSIONS: For older adults undergoing rehabilitation, greater functional improvement with the motivational techniques of Enhanced Medical Rehabilitation was contingent on patients having intact...
Eric J Lenze. American journal of physical medicine & rehabilitation. 2021-06-16 00:00:00
Ultrasonic Bone Scalpel (USBS) Does Not Reduce Blood Loss During Posterior Spinal Fusion (PSF) in Patients with Adolescent Idiopathic Scoliosis (AIS): Randomized Clinical Trial
CONCLUSION: There was no clinically significant difference in total blood loss, EBL/level, or complications between the two groups. In contrast to reports from other centers, at our high-volume spi...
Patrick Carry. Spine. 2021-06-08 00:00:00
A novel computational technique for the quantification of temporal summation in healthy individuals
CONCLUSIONS: Sumsquare outcome offers greater sensitivity than Windup Ratio for detecting changes in experimentally induced central sensitization. These findings introduce a novel method for assess...
Srbely John Z. Musculoskeletal science & practice. 2021-05-22 00:00:00
Effectiveness of a manual therapy protocol based on articulatory techniques in migraine patients. A randomized controlled trial
CONCLUSIONS: The application of a manual therapy protocol based on articulatory techniques reduced pain intensity, migraine disability, and medication intake, while improving quality of life in pat...
Gemma V Espí-López. Musculoskeletal science & practice. 2021-05-14 00:00:00
The efficacy of an educational movie to improve pain and dysfunctional behavior in school children: A randomized controlled trial
CONCLUSIONS: Educational movies may be an effective tool for educating students about pain management. However, the knowledge gained may not be sufficient to improve pain behaviour and intensity ov...
Julia Wager. European journal of pain (London, England). 2021-05-05 00:00:00
Lumbar Bracing for Chronic Low Back Pain: A Randomized Controlled Trial
CONCLUSIONS: In patients with uncomplicated chronic low back pain, a back brace when combined with education and exercise instruction did not provide any pain relief compared with education and exe...
Jason Petrasic. American journal of physical medicine & rehabilitation. 2021-03-31 00:00:00
A Comparison of Genicular Nerve Blockade With Corticosteroids Using Either Classical Anatomical Targets vs Revised Targets for Pain and Function in Knee Osteoarthritis: A Double-Blind, Randomized C...
CONCLUSIONS: The revised technique allowed more pain relief as well as greater proportion of successful responders at 1-hour post intervention. The large volume injected during therapeutic GNB coul...
Olivier Cornu. Pain medicine (Malden, Mass.). 2021-03-27 00:00:00
Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial
CONCLUSIONS: Visually changing the CRPS hand to a desired appearance modulates BPD and pain suggesting therapeutic potential for those with refractory CRPS. Further research to optimize this therap...
Candida S McCabe. European journal of pain (London, England). 2021-03-24 00:00:00
The catastrophization effects of an MRI report on the patient and surgeon and the benefits of 'clinical reporting': results from an RCT and blinded trials
CONCLUSION: Routine MRI reports produce a negative perception and poor functional outcomes in LBP. Focussed clinical reporting had significant benefits, which calls for the need for 'clinical r...
Mugesh Kanna Rishi. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-03-22 00:00:00
Changes of Opioid Consumption After Lumbar Fusion Using Ultrasound-Guided Lumbar Erector Spinae Plane Block: A Randomized Controlled Trial
CONCLUSIONS: Ultrasound-guided lumbar ESPB reduces the amount of analgesics required during and after lumbar fusion and reduces the postoperative Visual Analog Scale pain score.
Jun Li. Pain physician. 2021-03-19 00:00:00
Efficacy and Safety of Radiofrequency Thermocoagulation with Different Puncture Methods for Treatment of V1 Trigeminal Neuralgia: A Prospective Study
CONCLUSION: The transverse puncture method during radiofrequency thermocoagulation through the supraorbital foramen had better efficacy and fewer complications in comparison with the vertical punct...
Keyue Xie. Pain physician. 2021-03-19 00:00:00
Effectiveness of Dry Needling with Percutaneous Electrical Nerve Stimulation of High Frequency Versus Low Frequency in Patients with Myofascial Neck Pain
CONCLUSIONS: Low and high frequency percutaneous electrical nerve stimulation combined with deep dry needling showed similar effects, since no differences between groups were observed on any of the...
Hector Beltran Alacreu. Pain physician. 2021-03-19 00:00:00
Efficacy of Genicular Nerve Radiofrequency Ablation Versus Intra-Articular Platelet Rich Plasma in Chronic Knee Osteoarthritis: A Single-Blind Randomized Clinical Trial
CONCLUSION: Pulsed radiofrequency of the genicular nerves can be considered superior to knee intraarticular platelet-rich plasma injection for sustained pain relief and the lower severity index in...
Manal Hassanien. Pain physician. 2021-03-19 00:00:00
Comparative Effectiveness of Parasagittal Interlaminar and Transforaminal Cervical Epidural Steroid Injection in Patients with Cervical Radicular Pain: A Randomized Clinical Trial
CONCLUSIONS: Parasagittal IL ESI may be recommended over the TF ESI in reducing cervical radicular pain, considering both clinical effectiveness and safety.
Seong-Soo Choi. Pain physician. 2021-03-19 00:00:00


RCTs from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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Latest Systematic Reviews [2]

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Repetitive transcranial magnetic stimulation for fibromyalgia patients: A Systematic Review with Meta-Analysis
CONCLUSION: This study demonstrated that rTMS relieved pain and enhanced quality of life of patients with fibromyalgia; however, it did not improve anxiety, depression, and other symptoms based on...
Rui Qi. Pain medicine (Malden, Mass.). 2021-09-20 00:00:00
Comparison of interventions and outcomes of enhanced recovery after surgery: a systematic review and meta-analysis of 2456 adolescent idiopathic scoliosis cases
CONCLUSIONS: Use of ERAS after AIS is safe and effective, decreasing surgical duration and blood loss. ERAS methodology effectively focused on reducing time to first ambulation, PCA discontinuation...
David E Lebel. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-09-15 00:00:00
Behavioral outcomes of complete Freund's adjuvant-induced inflammatory pain in the rodent hind-paw: a systematic review and meta-analysis
Many analgesics inadequately address the psychiatric comorbidities of chronic and persistent pain, but there is no standard preclinical model of pain-altered behavior to support the development of...
Jose A Morón. Pain. 2021-09-12 00:00:00
Measurement properties of grimace scales for pain assessment in non-human mammals: a systematic review
Facial expressions of pain have been identified in several animal species. The aim of this systematic review was to provide evidence on the measurement properties of grimace scales for pain assessm...
Paulo V Steagall. Pain. 2021-09-12 00:00:00
Do external supports influence proprioception in patients with chronic ankle instability? A systematic review and meta-analyses
CONCLUSION: Applying external support has statistically significant negative effects on kinesthesia and a positive effect on the active JPS in the injured ankles of patients with CAI. However, this...
Yinghui Hua. American journal of physical medicine & rehabilitation. 2021-09-11 00:00:00
Pragmatic trials of pain therapies: a systematic review of methods
Pragmatic randomised clinical trials aim to directly inform clinical or health policy decision making. Here, we systematically review methods and design of pragmatic trials of pain therapies to exa...
Andrew S C Rice. Pain. 2021-09-07 00:00:00
Intraoperative Methadone Use in Cardiac Surgery: A Systematic Review
CONCLUSIONS: Intraoperative methadone use reduces acute postoperative pain and lowers opioid consumption in comparison to morphine and fentanyl. Initial results suggest that methadone may be an equ...
Marshall L C Roll. Pain medicine (Malden, Mass.). 2021-09-06 00:00:00
Systematic review of motor function scales and patient reported outcomes in spinal muscular atrophy
Spinal muscular atrophy (SMA) is a heterogeneous disease that results in loss of motor function. In an evolving treatment landscape, establishing the suitability and limitations of existing motor f...
Renee Haldenby. American journal of physical medicine & rehabilitation. 2021-09-06 00:00:00
Metabolic cost and performance of athletes with lower limb amputation and non-amputee matched controls during running: a systematic review
The elastic function of Running-Specific Prostheses (RSPs) likely contributes to a lower metabolic cost of running. However, it remains unclear whether RSPs provide advantages concerning the metabo...
Rodrigo Sudatti Delevatti. American journal of physical medicine & rehabilitation. 2021-09-06 00:00:00
Do patients with acute low back pain in emergency departments have more severe symptoms than those in general practice? A systematic review with meta-analysis
CONCLUSION: Patients with acute non-specific low back pain presenting to emergency departments may report higher levels of pain and disability than those seen in general practice.
Gustavo C Machado. Pain medicine (Malden, Mass.). 2021-09-04 00:00:00
The prevalence of depression in degenerative spine disease patients: A systematic review and meta-analysis
CONCLUSION: The systematic review indicated increased prevalence of depression in DSD patients. In consideration of the relationship between depression and poor surgical outcome, we should pay more...
Zhou Xiang. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-09-03 00:00:00
Intraoperative Ultrasound in Spine Decompression Surgery: A Systematic Review
CONCLUSIONS: The systematic review examines the current literature on IOUS and spinal decompression surgery. We identified a common qualitative definition for adequate decompression involving a &qu...
Jeremie Larouche. Spine. 2021-09-02 00:00:00
A systematic review and meta-analysis investigating the pain-relieving effect of interferential current on musculoskeletal pain
CONCLUSION: IFC alone is better than placebo at discharge. However, the low number of studies raises suspicions about this conclusion. IFC alone or added to other interventions is not more effectiv...
Omar W Althomali. American journal of physical medicine & rehabilitation. 2021-09-01 00:00:00
Efficacy of Hounsfield Units Measured by Lumbar Computer Tomography on Bone Density Assessment: A Systematic Review
CONCLUSIONS: Present data evidence favorable results regarding the possibility of establishing a threshold value for osteoporosis diagnosis from CT measurements of HU. Prospective large-scale studi...
António Miranda. Spine. 2021-09-01 00:00:00
Temporal changes in pain processing after whiplash injury, based on Quantitative Sensory Testing: A systematic review
CONCLUSIONS: Differences in pain processing between recovering and non-recovering patients can be observed already in the acute phase. Early screening for signs of altered pain processing can ident...
Iris Coppieters. European journal of pain (London, England). 2021-08-31 00:00:00


Reviews from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

View more articles