WikiMSK:Updates

Latest RCTs

Are Stabilisation Exercises Effective After Epidural Steroid Injection in Patients With Cervical Radiculopathy? A Prospective Randomised Controlled Trial: CONCLUSIONS: Stabilisation exercise programme, especially neck stabilisation, should be included after ILESI treatment due to positive effects on treatment outcomes.; Savas Sencan. European journal of pain (London, England). 2025-01-08 00:00:00
Efficacy of Higher-Voltage Long-Duration Pulsed Radiofrequency for Spinal Zoster-Associated Pain: A Randomized Controlled Trial: CONCLUSIONS: Using higher voltage in original HL-PRF treatments enhances pain relief, quality of life, and emotional well-being, in addition to reducing medication dependence. Multiple sessions mig...; Ling Ye. Pain physician. 2024-12-17 00:00:00
Effect of Epidural Volume Extension Using Low-Dose Sufentanil Combined with Low-Concentration Ropivacaine on Visceral Pain During Cesarean Sections: A Randomized Trial: CONCLUSIONS: EVE at 15 minutes after spinal anesthesia with a 10 mL combination of low-dose sufentanil (10 mu-g) and low-concentration (0.15%) ropivacaine can effectively reduce the incidence and s...; Chang-Na Wei. Pain physician. 2024-12-17 00:00:00
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block, Paravertebral Block and Quadratus Lumborum Block for Pelvi-ureteric Surgeries: A Randomized Double-Blind, Noninferiority Trial: CONCLUSIONS: In pelvi-ureteric surgeries, the ESPB, TPVB, and QLB provided comparable intraoperative and postoperative analgesia, patient satisfaction, and postoperative complications, but the ESPB...; Sherif Kamal Arafa. Pain physician. 2024-12-17 00:00:00
Comparative Study Between the Analgesic Effect of Prednisolone and Pregabalin in Managing Post Dural Puncture Headache After Lower Limb Surgeries: CONCLUSION: Both oral prednisolone and pregabalin were effective in reducing PDPH severity; oral pregabalin is superior to prednisolone.; Sherif M Mowafy. Pain physician. 2024-12-17 00:00:00
Dry Needling Plus Cervical Interlaminar Epidural Steroid Injections: Do We Have More Favorable Results in Cervical Disc Herniation? A Randomized Sham-Controlled Clinical Study: CONCLUSIONS: Combination therapy with dry needling has superiority to interlaminar epidural steroid injection + sham dry needling and only interlaminar epidural steroid injection groups in reducing...; Osman Hakan Gunduz. American journal of physical medicine & rehabilitation. 2024-12-13 00:00:00
E-52862-A selective sigma-1 receptor antagonist, in peripheral neuropathic pain: Two randomized, double-blind, phase 2 studies in patients with chronic postsurgical pain and painful diabetic neurop...: CONCLUSIONS: E-52862 demonstrated superior relief of CPSP vs. placebo after 4 weeks. Reductions in pain intensity were seen in PDN with E-52862; high placebo response rates may have prevented diffe...; Didier Bouhassira. European journal of pain (London, England). 2024-12-04 00:00:00
A Randomized Double-blind Trial of 5% Dextrose Versus Corticosteroid Hydrodissection for Meralgia Paresthetica: CONCLUSIONS: Ultrasound-guided perineural injection therapy of D5W is more beneficial than corticosteroid injection for MP at 4 to 6 months posttreatment. Additionally, D5W displays a better safety...; Ling Bai. Pain physician. 2024-12-02 00:00:00
Intravenous Versus Peribulbar Dexmedetomidine as an Adjunct to Local Anesthetics in Strabismus Surgery: A Randomized, Double-blinded Clinical Trial: CONCLUSION: Peribulbar dexmedetomidine outperforms intravenous dexmedetomidine in terms of postoperative analgesia and motor block duration when used as an adjunct to peribulbar anesthesia for stra...; Mohamed A Alazhary. Pain physician. 2024-12-02 00:00:00
Comparison Between Multimedia and Written Informed Consent for Lumbar Transforaminal Epidural Steroid Injection: A Randomized Controlled Pilot Trial: CONCLUSION: This pilot study contributes to the growing evidence supporting the use of multimedia consent to enhance patient understanding and reduce anxiety, marking a promising direction for impr...; Pyung Bok Lee. Pain physician. 2024-12-02 00:00:00
Dose Equivalence of Remimazolam and Propofol for Loss of Consciousness in Pediatric Patients: A Randomized Clinical Trial: CONCLUSIONS: Remimazolam demonstrates significantly higher sedative efficacy for pediatric patients than does propofol. An induction dose of 0.34 mg/kg-1 remimazolam could be recommended for genera...; Ma-Zhong Zhang. Pain physician. 2024-12-02 00:00:00
Good vibes for the brain - Placebo versus real vibration in patients with chronic neck pain: A randomized cross-over study: CONCLUSION: The study demonstrates the efficacy of neck muscle vibration to decrease neck pain and improve cervical joint position sense in patients with chronic neck pain. Nevertheless, the influe...; Konstantin Beinert. Musculoskeletal science & practice. 2024-11-09 00:00:00
How initial perceptions of the effectiveness of mind and body complementary and integrative health therapies influence long-term adherence in a pragmatic trial: CONCLUSIONS: Pragmatic pain trials should examine factors associated with engagement across assigned treatment protocols, especially if any of the treatment protocols being tested are sensitive to...; Stephanie L Taylor. Pain medicine (Malden, Mass.). 2024-11-08 00:00:00
Do mindfulness interventions cause harm? Findings from the Learning to Apply Mindfulness to Pain (LAMP) Pragmatic Clinical Trial: CONCLUSIONS: MBIs do not appear to cause harm, in terms of increased symptoms, for this population of patients with chronic pain and high levels of mental health comorbidities.; Brent C Taylor. Pain medicine (Malden, Mass.). 2024-11-08 00:00:00
The implementation of a pain navigator program in the department of Veterans Affairs' (VA) health care systems: a cluster randomized pragmatic clinical trial: CONCLUSIONS: Implementation of the telehealth delivered PNP provides a nuanced understanding of the introduction of novel care programs within diverse clinical settings. These findings are most app...; Susan N Hastings. Pain medicine (Malden, Mass.). 2024-11-08 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. RCTs from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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Latest Systematic Reviews

Optimizing Surgical Strategies: A Systematic Review of the Effectiveness of Preoperative Arterial Embolization for Hypervascular Metastatic Spinal Tumors: CONCLUSIONS: Preoperative arterial embolization of metastatic tumors to the spine has a relatively mild effect in reducing blood loss and improving patient survival. No effect was observed for preo...; Daniel Lubelski. The spine journal : official journal of the North American Spine Society. 2025-01-15 00:00:00
Aerobic Exercise Prescription for Pain Reduction in Fibromyalgia: A Systematic Review and Meta-Analysis: CONCLUSIONS: The study findings underscore the efficacy of aerobic exercise in alleviating pain among fibromyalgia patients, advocating for tailored exercise dosing to optimise adherence and outcomes.; Jose Manuel Jurado-Castro. European journal of pain (London, England). 2025-01-13 00:00:00
Cost-Utility of Lumbar Interbody Fusion Surgery: A Systematic Review: CONCLUSIONS: This is the first systematic review to comprehensively assess CUAs of all LIF approaches in the existing literature. While certain approaches, such as ALIF and OLIF, may demonstrate fa...; Vance Gardner. The spine journal : official journal of the North American Spine Society. 2025-01-13 00:00:00
Effectiveness of cognitive functional therapy (CFT) for chronic spinal pain: a systematic review with meta-analysis: CONCLUSION: CFT may offer clinically relevant benefits for CLBP, although the evidence remains mainly of low to very low certainty. Well-conducted studies, particularly in CNP and other spinal pain...; Silvia Bargeri. Pain medicine (Malden, Mass.). 2025-01-12 00:00:00
Deep Brain Stimulation (DBS) and Motor Cortex Stimulation (MCS) for Central Post-Stroke Pain: A Systematic Review And Meta-Analysis: CONCLUSION: The use of neurosurgical interventions such as DBS and MCS are last-resort treatments for Central Post-Stroke Pain, with limited studies exploring and comparing these two techniques. Wh...; Alex Green. Pain medicine (Malden, Mass.). 2025-01-11 00:00:00
Correction to The predictive power of the Roussouly classification on mechanical complications after surgery for adult spinal deformity: systematic review and meta-analysis: No abstract; Amer Sebaaly. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-01-10 00:00:00
Trigeminal neuralgia as a presentation of high cervical stenosis: a systematic review of the literature: CONCLUSION: Besides common manifestations, high cervical stenosis can cause trigeminal neuralgia. This case report and systematic review confirms spinal decompression and fusion surgery may be effe...; A A Baaj. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-01-10 00:00:00
Limited Evidence of Functional Benefit After Upper Limb Botulinum Toxin Treatment in Children With Cerebral Palsy: Systematic Review and Meta-analysis: CONCLUSIONS: Results suggest that upper limb botulinum toxin treatment is effective to decrease muscle tone, but functional benefits are not clearly established. The discrepancy between subjective...; Tamás Terebessy. American journal of physical medicine & rehabilitation. 2025-01-10 00:00:00
Platelet-Rich Plasma Versus Corticosteroids in the Treatment of Plantar Fasciitis: A Systematic Review and Meta-Analysis: CONCLUSIONS: PRP injections offer superior pain control compared to corticosteroids in the medium term (3-6 months) but not in the short term or at one year.; Lin Wang. American journal of physical medicine & rehabilitation. 2025-01-08 00:00:00
Effectiveness of amnion allograph injections in patients with degenerative musculoskeletal diseases: a systematic review and meta-analysis: CONCLUSIONS: Results indicated that amnion allograft injections produced significant pain reduction, functional improvement, and QoL enhancement in patients receiving injections compared to control...; Su-Ru Chen. American journal of physical medicine & rehabilitation. 2025-01-08 00:00:00
Clinical applications of 3D printing in spine surgery: a systematic review: CONCLUSIONS: 3D printing in spine surgery, a rapidly growing area of research, is predominantly used for creating drill guides for screw insertion, anatomical models, and innovative implants, enhan...; Peter Endre Eltes. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-01-08 00:00:00
Effects of Exercise on Pain and Disability after Lumbar Disc Herniation Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials: CONCLUSIONS: Exercise after LDH surgery was effective in reducing pain and disability and improving QoL.; Justin Y Jeon. American journal of physical medicine & rehabilitation. 2025-01-08 00:00:00
Physical Activity and Exercise Interventions in Abdominal Wall Hernia Patients: Impact on Quality of Life and Health Outcomes - A Systematic Review and Meta-Analysis: CONCLUSION: This systematic review and meta-analysis offer promising insights into the potential benefits of physical activity and exercise interventions on health outcomes for AWH patients.; Y Borja Sañudo Corrales. American journal of physical medicine & rehabilitation. 2025-01-08 00:00:00
Cervical musculoskeletal impairments in migraine and tension-type headache and relationship to pain related factors: An updated systematic review and meta-analysis: CONCLUSIONS: Several cervical musculoskeletal impairments are present in migraine and tension-type headache with very low certainty. Caution is needed since few studies considered factors that woul...; Lucy Thomas. Musculoskeletal science & practice. 2025-01-05 00:00:00
The economic burden of diabetes in spinal fusion surgery: a systematic review and meta-analysis: CONCLUSION: Patients with diabetes undergoing spinal fusion surgery had increased costs, prolonged LOS, increased 30-day/90-day readmission rates, and more frequent non-routine discharges.; James S Harrop. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-01-03 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. Reviews from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

Pubmed Link