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Latest RCTs [1]

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Integrated Meditation and Exercise Therapy: A Randomized Controlled Pilot of a Combined Nonpharmacological Intervention Focused on Reducing Disability and Pain in Patients with Chronic Low Back Pain: CONCLUSION: . Overall, 4 weeks of MedExT produced suggestive between-group trends for disability, significant between-group differences for measures of pain, and significant within-group increases...; Benedict J Kolber. Pain medicine (Malden, Mass.). 2021-02-23 00:00:00
Effect of Pain Education, Cryotherapy, and Transcutaneous Electrical Nerve Stimulation on the Pain, Functional Capacity, and Quality of Life in Patients With Nonspecific Chronic Low Back Pain: A Si...: CONCLUSIONS: This study showed that with pain education, there was no difference between cryotherapy and transcutaneous electrical nerve stimulation alone, combined, or placebo mode in improving pa...; Wouber Herickson de Brito Vieira. American journal of physical medicine & rehabilitation. 2021-02-17 00:00:00
Benefits of Adding Gluteal Dry Needling to a Four-Week Physical Exercise Program in a Chronic Low Back Pain Population. A Randomized Clinical Trial: CONCLUSIONS: In chronic low back patients, adding dry needling to a four-week exercise program has an additional benefit in pain and sensitivity compared with adding sham dry needling to the same e...; Daniel Pecos-Martín. Pain medicine (Malden, Mass.). 2021-02-13 00:00:00
Effect of Drug Disposal Kits and Fact Sheets on Elimination of Leftover Prescription Opioids: The DISPOSE Multi-Arm Randomized Controlled Trial: CONCLUSIONS: These findings suggest that passive provision of a drug disposal kit at prescription pickup did not increase rates of leftover opioid disposal when compared with provision of a fact sh...; Constance L Monitto. Pain medicine (Malden, Mass.). 2021-02-12 00:00:00
Short-Term Effect of Scalp Acupuncture on Pain, Sleep Disorders, and Quality of Life in Patients with Temporomandibular Disorders: A A Randomized Clinical Trial: CONCLUSIONS: The scalp acupuncture proved to be another alternative for pain relief in patients with TMD, demonstrating positive results in the short term. However, it was not as effective in impro...; Gustavo Augusto Seabra Barbosa. Pain medicine (Malden, Mass.). 2021-02-09 00:00:00
Efficacy and Long-term Effect of Radiofrequency Denervation in Patients with Clinically Diagnosed Cervical Facet Joint Pain: A Double-blind Randomized Controlled Trial: CONCLUSIONS: We did not observe significant differences between RF denervation combined with injection of local anesthesia compared with local anesthesia only at 6 months follow-up. We found a diff...; Sander M J van Kuijk. Spine. 2021-02-03 00:00:00
Effectiveness of a structured group intervention based on pain neuroscience education for patients with fibromyalgia in primary care: A multicentre randomized open-label controlled trial: CONCLUSIONS: In this sample of patients with FM, the improvement in quality of life and control of symptoms obtained by adding a PNE intervention showed promising results, equalling or surpassing p...; FIMIDOC Working Group researchers. European journal of pain (London, England). 2021-01-29 00:00:00
Mindful Self-Compassion program for chronic pain patients: A randomized controlled trial: CONCLUSIONS: Mindful Self-Compassion is an appropriate therapeutic approach for CP patients and may result in greater benefits on self-compassion and emotional well-being than CBT.; Ángela Palao-Tarrero. European journal of pain (London, England). 2021-01-20 00:00:00
Internet-delivered acceptance and commitment therapy as microlearning for chronic pain: A randomized controlled trial with 1-year follow-up: CONCLUSIONS: Internet-ACT as microlearning may improve a broad range of outcomes in chronic pain.; Rikard K Wicksell. European journal of pain (London, England). 2021-01-18 00:00:00
Brief preoperative mind-body therapies for total joint arthroplasty patients: a randomized controlled trial: Although knee and hip replacements are intended to relieve pain and improve function, up to 44% of knee replacement patients and 27% of hip replacement patients report persistent postoperative join...; Eric L Garland. Pain. 2021-01-15 00:00:00
Photobiomodulation therapy is not better than placebo in patients with chronic nonspecific low back pain: a randomised placebo-controlled trial: Photobiomodulation therapy (PBMT) has been used in several musculoskeletal disorders to reduce pain, inflammation, and promoting tissue regeneration. The current evidence about the effects of PBMT...; Shaiane Silva Tomazoni. Pain. 2021-01-15 00:00:00
Effect of anodal high-definition transcranial direct current stimulation on the pain sensitivity in a healthy population: a double-blind, sham-controlled study: High-definition transcranial direct current stimulation (HD-tDCS) of brain areas related to pain processing may provide analgesic effects evident in the sensory detection and pain thresholds. The s...; Thomas Graven-Nielsen. Pain. 2021-01-15 00:00:00
Conditioned open-label placebo for opioid reduction after spine surgery: a randomized controlled trial: Placebo effects have traditionally involved concealment or deception. However, recent evidence suggests that placebo effects can also be elicited when prescribed transparently as "open-label p...; Kristin L Schreiber. Pain. 2021-01-15 00:00:00
Ultrasound-guided transversus abdominis plane block vs trigger point injections for chronic abdominal wall pain: a randomized clinical trial: The primary aim of this randomized clinical trial is to investigate the effects of ultrasound-guided transversus abdominis plane (TAP) vs ultrasound-guided trigger point injections (TPIs) on numeri...; W Michael Hooten. Pain. 2021-01-12 00:00:00
Predictive Factors Affecting Surgical Outcomes in Patients with Degenerative Lumbar Spondylolisthesis: CONCLUSION: While the degree of vertebral slippage and the presence of angulation were not associated with poor recovery after surgery for lumbar degenerative spondylolisthesis, postoperative outco...; Atsushi Okawa. Spine. 2021-01-11 00:00:00

RCTs from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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Latest Systematic Reviews [2]

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Early Predictors of Neurological Outcomes After Traumatic Spinal Cord Injury: A Systematic Review and Proposal of a Conceptual Framework: CONCLUSIONS: This study provides a comprehensive review of predictors of neurological outcomes after traumatic spinal cord injury. It also highlights the heterogeneity of outcomes used by studies t...; Jean-Marc Mac-Thiong. American journal of physical medicine & rehabilitation. 2021-06-16 00:00:00
Perioperative factors associated with persistent post-surgical pain after hysterectomy, cesarean section, prostatectomy, and donor nephrectomy: a systematic review and meta-analysis: Persistent postsurgical pain (PPSP) is a common, and often disabling postoperative morbidity, but many questions remain about factors associated with PPSP. This systematic review and meta-analysis...; Simon Haroutounian. Pain. 2021-06-14 00:00:00
The Relationship of Aging and Smoking with Rotator Cuff Disease: A Systematic Review and Meta-Analysis: CONCLUSION: In this systematic review and meta-analysis, increasing age was a strong risk factor for rotator cuff disease. The finding that current smokers are more likely to have rotator cuff dise...; Nitin B Jain. American journal of physical medicine & rehabilitation. 2021-06-14 00:00:00
Changes in kinematics, kinetics, and muscle activity in patients with lumbar spinal stenosis during gait: systematic review: CONCLUSION: Although numerous studies have investigated gait function in patients with LSS, gait alterations in joint kinetics and muscle activity over time remain largely unknown. In addition, the...; Erin M Mannen. The spine journal : official journal of the North American Spine Society. 2021-06-11 00:00:00
Which traumatic spinal injury creates which degree of instability? A systematic quantitative review: CONCLUSIONS: Specific traumatic spinal injuries produce characteristic but complex three-dimensional degrees of instability, which depend on the type, level, and morphology of the injury. Future st...; Hans-Joachim Wilke. The spine journal : official journal of the North American Spine Society. 2021-06-11 00:00:00
Dry Needling versus Trigger Point Injection for Neck Pain Symptoms Associated with Myofascial Trigger Points: A Systematic Review and Meta-analysis: CONCLUSION: Low evidence suggests a superior effect of TrP injection (wet needling) for decreasing pain of cervical muscle TrPs at short-term as compared to dry needling. No significant effects on...; Gustavo Plaza-Manzano. Pain medicine (Malden, Mass.). 2021-06-11 00:00:00
The association between pain scores and disc height change following discectomy surgery in lumbar disc herniation patients: a systematic review and meta-analysis: CONCLUSION: Discectomy surgery produces significant and quantifiable reductions in DH and DHI. Additionally, the reduction in DH is responsible for the decrease in back pain scores post discectomy,...; Ashish D Diwan. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-06-11 00:00:00
Evaluation of open and minimally invasive spinal surgery for the treatment of thoracolumbar metastatic epidural spinal cord compression: a systematic review: CONCLUSION: MESCC carries significant morbidity and mortality. Surgical approaches for palliative treatment should account for this fact. We conclude that MIS techniques offer a viable alternative...; Bruce Frankel. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-05-30 00:00:00
Mathematical and computational models for pain: a systematic review: CONCLUSIONS: Although understudied, the development of mathematical models may augment the current understanding of pain by providing directions for testable hypotheses of its underlying mechanisms...; Max Ortiz-Catalan. Pain medicine (Malden, Mass.). 2021-05-29 00:00:00
Placebo effects in low back pain; a systematic review and meta-analysis of the literature: CONCLUSIONS: This review shows a significant contribution of placebo effects to chronic LBP symptom relief in clinical and experimental conditions. The meta-analysis revealed that placebo effects c...; K M Szadek. European journal of pain (London, England). 2021-05-29 00:00:00
Management of spinal aneurysms associated with arteriovenous malformations: systematic literature review and illustrative case: CONCLUSIONS: The treatment strategy for AVM-associated spinal aneurysms should be tailored on the single patient. In presence of large aneurysms that cause mass-effect symptoms, when rupture of the...; Pietro Fiaschi. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-05-27 00:00:00
Perioperative outcomes following preoperative epidural analgesia in hip fracture patients undergoing surgical repair: A systematic review: CONCLUSIONS: Preoperative epidural analgesia for hip fracture may reduce perioperative cardiac events and mortality, but the number of included studies in this systematic review was low. More resea...; Susan M Lee. Pain medicine (Malden, Mass.). 2021-05-22 00:00:00
The association between vertebral endplate structural defects and back pain: a systematic review and meta-analysis: CONCLUSION: Overall, there is moderate quality evidence of an association between back pain and endplate structural defects, which is most evident for erosion, sclerosis and Schmorl's nodes. Go...; Michele C Battié. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-05-22 00:00:00
The role of TaqI, ApaI and BsmI polymorphisms of VDR gene in lumbar spine pathologies: systematic review and meta-analysis: CONCLUSIONS: Our findings indicate that TaqI and ApaI polymorphisms of the VDR gene are important risk factors for developing lumbar spine pathologies. Moreover, the TaqI polymorphism is a risk fac...; Nonanzit Pérez-Hernández. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2021-05-22 00:00:00
A Systematic Review of Practiced-Based Research of Complementary and Integrative Health Therapies as Provided for Pain Management in Clinical Settings: Recommendations for the Future and A Call to...: CONCLUSIONS: Findings from this systematic review of practice-based, real-word research indicate that CIH therapies exert positive effects on various pain outcomes. Although all studies reported be...; Jeffery A Dusek. Pain medicine (Malden, Mass.). 2021-05-19 00:00:00

Reviews from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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