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Small Fibre Neuropathy
Small fiber neuropathy (SFN) is a painful neuropathy involving selectively the Aฮด and C nerve fibres. This leads to sensory, autonomic, or combined symptoms. Small fibre neuropathy (SFN) and large fibre neuropathy belong to a group of diseases known as peripheral neuropathies. Polyneuropathy refers to cases where either the large fibres are affected, or both the large and small fibres are affected. SFN refers to isolated small fibre involvement. About 40-50% of patient with fibromyalgia meet the diagnostic criteria for SFN - Read More
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Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES)
The Lancet Rheumatology
ABSTRACT - This study compared the clinical and cost-effectiveness of transforaminal epidural steroid injection (TFESI) and surgical microdiscectomy for treating sciatica secondary to herniated lumbar discs. The randomized controlled trial involved 163 patients across 11 UK spinal units. At 18 weeks, the primary outcome of Oswestry Disability Questionnaire (ODQ) scores showed no significant difference between the TFESI and surgery groups. However, surgery had a higher rate of serious adverse events and was less cost-effective compared to TFESI. The researchers concluded that for patients with sciatica secondary to herniated lumbar discs and symptom duration up to 12 months, TFESI should be considered as the first invasive treatment option.
“I will respect the hard-won scientific gains of those physicians in whose steps I walk, and gladly share such knowledge as is mine with those who are to follow.”
— The Hippocratic Oath: Modern Version, Lasagna 1964