EBQ:Twin Spine Study

From WikiMSK

Battie M, et al. "The Twin Spine Study: Contributions to a changing view of disc degeneration". The Spine Journal. 2009. 9:47-59.
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Clinical Question

What is the contribution of genetics to disc degeneration?

Conclusion

There is a substantial influence of heredity on lumbar disc degeneration. There is little effect on disc degeneration from occupational and leisuretime physical loading, and increased loading may have a small benefit. There is only a small effect from smoking. Body weight and muscle strength have modest effects on disc degeneration.

Design

Population Studied

Inclusion Criteria

Exclusion Criteria

Baseline Characteristics

Interventions

Outcomes/Results

Primary Outcomes

Secondary Outcomes

Adverse events

Discussion

Criticism

Funding

See Also