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Glyceryl Trinitrate: Difference between revisions
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Glyceryl Trinitrate is a treatment for [[Tendinopathy]]. It is applied to the degenerative area. There are two formulations in New Zealand. | Glyceryl Trinitrate is a treatment for [[Tendinopathy]]. It is applied to the degenerative area and may enhance collagen synthesis via the nitric oxide signaling molecule. There are two formulations in New Zealand. | ||
*Patches - | *Patches - 5mg/24 hour or 10mg/24 hour Nitroderm TTS patches are available. The literature describes using one-fourth to one-half of one of these doses but if you cut Nitroderm the medication leaks out. One can try use the full 5mg/24 hour dose or put medical tape under a portion of it. | ||
*Ointment - 0.2% Rectogesic. | *Ointment - 0.2% Rectogesic. | ||
==Benefits== | |||
It can take up to 12 to 24 weeks to experience significant improvement. | |||
==Adverse effects== | |||
Possible side effects are dizziness and headache. | |||
==Contraindications== | |||
*Hypotension | |||
*Migraine headaches | |||
*Rosacea | |||
*Head injury | |||
*Severe anaemia | |||
*Ingestion of phosphodiesterase inhibitors | |||
*Ingestion of oral or sublingual nitroglycerin | |||
==See Also== | |||
*[[Tendinopathy]] | |||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
Revision as of 08:03, 13 April 2022
This article is a stub.
Glyceryl Trinitrate is a treatment for Tendinopathy. It is applied to the degenerative area and may enhance collagen synthesis via the nitric oxide signaling molecule. There are two formulations in New Zealand.
- Patches - 5mg/24 hour or 10mg/24 hour Nitroderm TTS patches are available. The literature describes using one-fourth to one-half of one of these doses but if you cut Nitroderm the medication leaks out. One can try use the full 5mg/24 hour dose or put medical tape under a portion of it.
- Ointment - 0.2% Rectogesic.
Benefits
It can take up to 12 to 24 weeks to experience significant improvement.
Adverse effects
Possible side effects are dizziness and headache.
Contraindications
- Hypotension
- Migraine headaches
- Rosacea
- Head injury
- Severe anaemia
- Ingestion of phosphodiesterase inhibitors
- Ingestion of oral or sublingual nitroglycerin
