◔
Glyceryl Trinitrate
From WikiMSK
This article is a stub.
Glyceryl Trinitrate is a treatment for Tendinopathy. It is applied to the degenerative area and may enhance collagen synthesis via the nitric oxide signaling molecule.
Formulations
There are two formulations in New Zealand.
- Patches - 5mg/24 hour or 10mg/24 hour Nitroderm TTS patches are available. The literature describes using one-fourth to one-half of one of these doses but if you cut Nitroderm the medication leaks out. One can try use the full 5mg/24 hour dose or put medical tape under a portion of it.
- Ointment - 0.2% Rectogesic.
Benefits
It can take up to 12 to 24 weeks to experience significant improvement.
Adverse effects
Possible side effects are dizziness and headache.
Contraindications
- Hypotension
- Migraine headaches
- Rosacea
- Head injury
- Severe anaemia
- Ingestion of phosphodiesterase inhibitors
- Ingestion of oral or sublingual nitroglycerin
