Nociplastic Pain

From WikiMSK

Epidemiology

The prevalence of chronic pain in New Zealand, when defined as lasting for 6 months or longer, was measured at 16.9% in 2011. Prevalence increased with age and economic deprivation. Pacific and Asian peoples had lower rates of chronic pain than European/other.[1] Around one fifth of people with chronic pain have predominantly neuropathic pain.[citation needed] Neuropathic pain is more disabling than other forms of pain and is associated with a lower quality of life.[citation needed]

Definitions

IASP Definition of Pain

The IASP definition of pain was recently updated in 2020.[2]

An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage

—IASP Definition of Pain 2020
Central Sensitisation

Woolf discussed the differences between pain versus pathology versus "pain syndromes."[3]

Any sensory experience greater in amplitude, duration and spatial extent than that would be expected from a defined peripheral input under normal circumstances qualifies as potentially reflecting a central amplification due to increased excitation or reduced inhibition. These changes could include a reduction in threshold, exaggerated response to a noxious stimulus, pain after the end of a stimulus, and a spread of sensitivity to normal tissue

—Woolf 2011

Key Articles

  • {{#l:Cohen2016 - nociplastic pain third mechanistic descriptor.pdf}}
  • {{#l:Woolf2011 - Central sensitisation.pdf}}
  • {{#l:Woolf2014 - Nociceptive amplification naming.pdf}}
  • {{#l:Yunus2008 - Central sensitivity syndrome.pdf}}

References

  1. โ†‘ Dominick et al.. Patterns of chronic pain in the New Zealand population. The New Zealand medical journal 2011. 124:63-76. PMID: 21946879.
  2. โ†‘ International Association for the Study of Pain (2020) IASPโ€™s New Definition of Pain. Available at: https://www.iasp-pain.org/PublicationsNews/NewsDetail.aspx?ItemNumber=10475 (accessed 27 July 2020).
  3. โ†‘ Woolf. Central sensitization: implications for the diagnosis and treatment of pain. Pain 2011. 152:S2-15. PMID: 20961685. DOI. Full Text.