Sodium Channelopathies
From WikiMSK
Voltage gated sodium channels are transmembrane polypeptides with four domains. A pore is made with all four domains through which sodium can enter the cell. There is also an ancillary beta unit for anchoring and kinetics.
There are nine known members of sodium channels labelled Nav1.1 through Nav1.9. The associated genes are named SCN1A through SCN11A (the SCN6/7A gene is part of the Nax sub-family and has uncertain function)
