Template:Lower Limb Pain Neurogenic and Referred DDX: Difference between revisions

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***Diabetes Mellitus with autonomic neuropathy
***Diabetes Mellitus with autonomic neuropathy
***Diabetic amyotrophy {{#info: Probably a vasculitis aetiology with ischaemia followed by axonal degeneration and demyelination. Characterised by unilateral weakness, wasting, and pain, commonly in the quadriceps, then spreading later to the contralateral side asymmetrically.|note}}
***Diabetic amyotrophy {{#info: Probably a vasculitis aetiology with ischaemia followed by axonal degeneration and demyelination. Characterised by unilateral weakness, wasting, and pain, commonly in the quadriceps, then spreading later to the contralateral side asymmetrically.|note}}
**Vasculitis Neuropathy {{#info:vasculitis of the small and medium-sized vessels in the peripheral nervous system.|note}}
**Vasculitic Neuropathy {{#info:vasculitis of the small and medium-sized vessels in the peripheral nervous system.|note}}
***Primary vasculitides: Churg-Strauss syndrome, microscopic polyangiitis, classic polyarteritis nodosa and Wegener granulomatosis
***Primary vasculitides: Churg-Strauss syndrome, microscopic polyangiitis, classic polyarteritis nodosa and Wegener granulomatosis
***Secondary vasculitides: A complication of connective tissue disease (systemic lupus erythematosus, rheumatoid arthritis and Sjögren syndrome), infection (hepatitis B and C, human immunodeficiency virus, Lyme disease, cytomegalovirus, Herpes zoster virus and various bacterial infections), medication (sulphonamides, other antibiotics and anti-viral agents) and paraneoplastic vasculitis
***Secondary vasculitides: A complication of connective tissue disease (systemic lupus erythematosus, rheumatoid arthritis and Sjögren syndrome), infection (hepatitis B and C, human immunodeficiency virus, Lyme disease, cytomegalovirus, Herpes zoster virus and various bacterial infections), medication (sulphonamides, other antibiotics and anti-viral agents) and paraneoplastic vasculitis
**Paraneoplastic peripheral neuropathy {{#info:In addition to local effects and paraneoplastic vasculitis, can also get sensorimotor paraneoplastic neuropathy. May have anti-neuronal antibodies and EMG findings.|note}}
*Brain
**Multiple sclerosis
**Parkinson’s disease
**Motor neurone disease
**Post-stroke pain in lenticulo-capsular haemorrhages
**Space-occupying lesions.
*Spinal Cord
**Multiple sclerosis
**Motor neurone disease
**Syringomyelia
**Transverse myelitis
**Posterior or anterolateral situated space-occupying lesion (e.g. tumour, abscess, haematoma)
*Cervical and Thoracic Spinal Canal
**Any posterior or anterolateral space-occupying lesion (e.g. abscess, tumour, haematoma)
*Conus Medullaris
**Disc pathology
**Gas sequestration
**Tumours (soft tissue, intradural, extradural, bone, metastases)
*Lumbar Spine Canal
**Interspinous bursa
**Facet joint (OA, hypertrophy, cyst, rotational instability)
**Anterolisthesis or retrolisthesis
**Space-occupying lesion (disc pathology, haematoma, tumours)
*Lumbar Nerve Root Canal

Revision as of 18:31, 8 December 2020

  • Systemic Conditions
    • Metabolic Neuropathy
      • Diabetes Mellitus with distal symmetrical polyneuropathy
      • Diabetes Mellitus of other subtypes - proximal diabetes, truncal, cranial, median and ulnar neuropathies
      • Diabetes Mellitus with autonomic neuropathy
      • Diabetic amyotrophy Probably a vasculitis aetiology with ischaemia followed by axonal degeneration and demyelination. Characterised by unilateral weakness, wasting, and pain, commonly in the quadriceps, then spreading later to the contralateral side asymmetrically.
    • Vasculitic Neuropathy vasculitis of the small and medium-sized vessels in the peripheral nervous system.
      • Primary vasculitides: Churg-Strauss syndrome, microscopic polyangiitis, classic polyarteritis nodosa and Wegener granulomatosis
      • Secondary vasculitides: A complication of connective tissue disease (systemic lupus erythematosus, rheumatoid arthritis and Sjögren syndrome), infection (hepatitis B and C, human immunodeficiency virus, Lyme disease, cytomegalovirus, Herpes zoster virus and various bacterial infections), medication (sulphonamides, other antibiotics and anti-viral agents) and paraneoplastic vasculitis
    • Paraneoplastic peripheral neuropathy In addition to local effects and paraneoplastic vasculitis, can also get sensorimotor paraneoplastic neuropathy. May have anti-neuronal antibodies and EMG findings.
  • Brain
    • Multiple sclerosis
    • Parkinson’s disease
    • Motor neurone disease
    • Post-stroke pain in lenticulo-capsular haemorrhages
    • Space-occupying lesions.
  • Spinal Cord
    • Multiple sclerosis
    • Motor neurone disease
    • Syringomyelia
    • Transverse myelitis
    • Posterior or anterolateral situated space-occupying lesion (e.g. tumour, abscess, haematoma)
  • Cervical and Thoracic Spinal Canal
    • Any posterior or anterolateral space-occupying lesion (e.g. abscess, tumour, haematoma)
  • Conus Medullaris
    • Disc pathology
    • Gas sequestration
    • Tumours (soft tissue, intradural, extradural, bone, metastases)
  • Lumbar Spine Canal
    • Interspinous bursa
    • Facet joint (OA, hypertrophy, cyst, rotational instability)
    • Anterolisthesis or retrolisthesis
    • Space-occupying lesion (disc pathology, haematoma, tumours)
  • Lumbar Nerve Root Canal
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