First Carpometacarpal Joint Osteoarthritis

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Aetiology

The first CMCJ is highly mobile which is probably linked to an increased rate of degeneration. There is also an association with hypermobility

Epidemiology

Increases with age, most common in postmenopausal women. The female to male ratio is 6:1.1

Assessment

  • Base of thumb pain
  • Activity related particularly gripping, using taps and door knobs, unscrewing lids, turning keys, sewing.
  • Thumb weakness
Examination
  • Deformity at the base of the first MCPJ.
  • Adduction of the 1st metacarpal may occur which is visualised by a reduced 1st web space and hyperextension of MCPJ.
  • Palpate for tenderness, crepitation, and subluxation
  • Range of motion
  • Power, pincer strength may be reduced
  • Grind test: Hold the 1st metacarpal, move the thumb in a circular motion, and apply axial compression

Differential Diagnoses

Investigations

Xray Inflammatory and rheumatological blood tests if required.

Management

Activity Modification
Hand Therapy
Steroid Injection
Dextrose Injection
Steroid slightly more effective at one month, dextrose slightly more effective at six months.[1]
Surgery

References

  1. โ†‘ Jahangiri A, Moghaddam FR, Najafi S. Hypertonic dextrose versus corticosteroid local injection for the treatment of osteoarthritis in the first carpometacarpal joint: a double-blind randomized clinical trial. J Orthop Sci. 2014 Sep;19(5):737-43. doi: 10.1007/s00776-014-0587-2. Epub 2014 Aug 27. PMID: 25158896.

Literature Review