Hand Atrophy Differential Diagnosis

From WikiMSK

Causes of unilateral atrophy and weakness of intrinsic hand muscles

  • All intrinsic hand muscles
    • Combined ulnar neuropathy and carpal tunnel syndrome
    • Lower brachial plexopathy (including neurogenic thoracic outlet syndrome)
    • C8 radiculopathy
    • Amyotrophic lateral sclerosis
    • Focal motor neuron disease (monomelic amyotrophy)
    • Cervical syringomyelia
    • High cervical or foramen magnum spinal cord compression
    • Peripheral polyneuropathy
    • Distal myopathy
  • All intrinsic muscles excluding the thenar muscles
    • Ulnar neuropathy at the elbow
    • Ulnar neuropathy at the wrist (Guyonโ€™s canal)
  • All intrinsic muscles excluding the thenar and hypothenar muscles
    • Ulnar neuropathy at the wrist (distal Guyonโ€™s canal or pisohamate hiatus)
  • Limited to the thenar muscles
    • Carpal tunnel syndrome
    • High median neuropathy (including the pronator syndrome)
    • Neurogenic thoracic outlet syndrome
    • T1 radiculopathy