Template:DN4

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DN4 - Questionnaire
INTERVIEW OF THE PATIENT
QUESTION 1
Does the pain have one or more of the following characteristics? Yes No
Burning
Painful cold
Electric shocks
QUESTION 2
Is the pain associated with one or more of the following symptoms in the same area? Yes No
Tingling
Pins and needles
Numbness
Itching
EXAMINATION OF THE PATIENT
QUESTION 3
Is the pain located in an area where the physical examination may reveal one or more of the following characteristics? Yes No
Hypoaesthesia to touch
Hypoaesthesia to pinprick
QUESTION 4
In the painful area, can the pain be caused or increased by: Yes No
Brushing
Result
Negative
Score: 0/10
Validated in painful diabetic polyneuropathy. At the cut-off of 4, DN4 displayed sensitivity of 80%, specificity of 92%, positive predictive value (PPV) of 82%, negative predictive value (NPV) of 91%, and likelihood ratio for a positive result (LR(+) ) of 9.6. At the cut-off of 3, DN4-interview showed sensitivity and specificity of 84%, PPV of 71%, NPV of 92%, and LR(+) of 5.3.[1]
  1. โ†‘ Spallone V, Morganti R, D'Amato C, Greco C, Cacciotti L, Marfia GA. Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy. Diabet Med. 2012 May;29(5):578-85. doi: 10.1111/j.1464-5491.2011.03500.x. PMID