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Latest RCTs

A Randomized Double-blind Trial of 5% Dextrose Versus Corticosteroid Hydrodissection for Meralgia Paresthetica: CONCLUSIONS: Ultrasound-guided perineural injection therapy of D5W is more beneficial than corticosteroid injection for MP at 4 to 6 months posttreatment. Additionally, D5W displays a better safety...; Ling Bai. Pain physician. 2024-12-02 00:00:00
Intravenous Versus Peribulbar Dexmedetomidine as an Adjunct to Local Anesthetics in Strabismus Surgery: A Randomized, Double-blinded Clinical Trial: CONCLUSION: Peribulbar dexmedetomidine outperforms intravenous dexmedetomidine in terms of postoperative analgesia and motor block duration when used as an adjunct to peribulbar anesthesia for stra...; Mohamed A Alazhary. Pain physician. 2024-12-02 00:00:00
Comparison Between Multimedia and Written Informed Consent for Lumbar Transforaminal Epidural Steroid Injection: A Randomized Controlled Pilot Trial: CONCLUSION: This pilot study contributes to the growing evidence supporting the use of multimedia consent to enhance patient understanding and reduce anxiety, marking a promising direction for impr...; Pyung Bok Lee. Pain physician. 2024-12-02 00:00:00
Dose Equivalence of Remimazolam and Propofol for Loss of Consciousness in Pediatric Patients: A Randomized Clinical Trial: CONCLUSIONS: Remimazolam demonstrates significantly higher sedative efficacy for pediatric patients than does propofol. An induction dose of 0.34 mg/kg-1 remimazolam could be recommended for genera...; Ma-Zhong Zhang. Pain physician. 2024-12-02 00:00:00
Good vibes for the brain - Placebo versus real vibration in patients with chronic neck pain: A randomized cross-over study: CONCLUSION: The study demonstrates the efficacy of neck muscle vibration to decrease neck pain and improve cervical joint position sense in patients with chronic neck pain. Nevertheless, the influe...; Konstantin Beinert. Musculoskeletal science & practice. 2024-11-09 00:00:00
How initial perceptions of the effectiveness of mind and body complementary and integrative health therapies influence long-term adherence in a pragmatic trial: CONCLUSIONS: Pragmatic pain trials should examine factors associated with engagement across assigned treatment protocols, especially if any of the treatment protocols being tested are sensitive to...; Stephanie L Taylor. Pain medicine (Malden, Mass.). 2024-11-08 00:00:00
Do mindfulness interventions cause harm? Findings from the Learning to Apply Mindfulness to Pain (LAMP) Pragmatic Clinical Trial: CONCLUSIONS: MBIs do not appear to cause harm, in terms of increased symptoms, for this population of patients with chronic pain and high levels of mental health comorbidities.; Brent C Taylor. Pain medicine (Malden, Mass.). 2024-11-08 00:00:00
The implementation of a pain navigator program in the department of Veterans Affairs' (VA) health care systems: a cluster randomized pragmatic clinical trial: CONCLUSIONS: Implementation of the telehealth delivered PNP provides a nuanced understanding of the introduction of novel care programs within diverse clinical settings. These findings are most app...; Susan N Hastings. Pain medicine (Malden, Mass.). 2024-11-08 00:00:00
Immediate Correction of Idiopathic Scoliosis With Nighttime Braces Created by a Fully Automated Generative Design Algorithm: A Randomized Controlled Crossover Trial: CONCLUSION: The fully automated generative brace design algorithm proves to be clinically relevant, allowing for immediate in-brace correction equivalent to that of braces designed by expert orthot...; Carl-Éric Aubin. Spine. 2024-10-22 00:00:00
Percutaneous Intradiscal Radiofrequency Thermocoagulation Combined with Sinuvertebral Nerve Ablation for the Treatment of Discogenic Low Back Pain: CONCLUSIONS: In DLBP, the sinuvertebral nerve (SVN) is the main nerve involved in the lumbar disc pain signaling pathway, and compared with PIRFT and SVNA alone, combined PIRFT and SVNA treatment m...; Baorong He. Pain physician. 2024-10-01 00:00:00
Comparison of Ultrasound-guided Transverse Carpal Ligament Release via Different Approaches in Carpal Tunnel Syndrome: A Prospective, Randomized, Controlled Trial: CONCLUSIONS: Ultrasound-guided TCL needle release via the long-axis approach appears to be more effective than the short-axis approach for treating mild to moderate CTS.; Hailin Xu. Pain physician. 2024-10-01 00:00:00
Erector Spinae Plane Block Provided Comparable Analgesia as Thoracic Paravertebral Block Post Pediatric Nuss Procedure for Pectus Excavatum: A Randomized Controlled Trial: CONCLUSIONS: Preoperative ESPB, when combined with multimodal analgesia, was noninferior in analgesic effect compared with TPVB in terms of pain scores and opioid consumption in pediatric patients...; Jing Yang. Pain physician. 2024-10-01 00:00:00
Comparison of the Efficacy of Ultrasound-Guided Suprascapular Nerve Blocks and Intraarticular Corticosteroid Injections for Frozen Shoulder: A Randomized Controlled Trial: CONCLUSIONS: A combination of ultrasound-guided IACIs and physiotherapy should be attempted first as a frozen shoulder treatment.; Lin-Fen Hsieh. Pain physician. 2024-10-01 00:00:00
Pain neuroscience education is not superior to spinal physiology and ergonomics education within a short multidisciplinary rehabilitation program: A randomized controlled trial: CONCLUSION: There appears to be no advantage in replacing a conventional, non-neuroscientific educational program (based on spinal physiology and ergonomics) with a pain neuroscience education prog...; André Thevenon. Musculoskeletal science & practice. 2024-09-11 00:00:00
A combined program of education plus exercise versus general advice for ankle osteoarthritis: A feasibility randomised controlled trial: CONCLUSIONS: This study demonstrates that it is feasible to run an adequately powered RCT comparing physiotherapist-delivered education plus exercise versus physiotherapist-delivered general advice...; Bill Vicenzino. Musculoskeletal science & practice. 2024-09-06 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. RCTs from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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Latest Systematic Reviews

Regional Analgesia Techniques Following Thoracic Surgery: A Systematic Review and Network Meta-analysis: CONCLUSIONS: The cTEA and cSAPB techniques are more likely to reduce the cumulative opioid consumption within 24 hours. The cTEA, cSAPB, ESPB techniques were more likely to improve pain at postoper...; Dong Zhang. Pain physician. 2024-12-02 00:00:00
Mindfulness Meditation for Fibromyalgia Syndrome: A Systematic Review and Meta-analysis: CONCLUSIONS: Very low to moderate evidence shows that MM improves quality of life, relieves stress, and relieves insomnia and depression in patients with FMS in the short-term. Notably, the improve...; Minpeng Lu. Pain physician. 2024-12-02 00:00:00
Effectiveness and Safety of Hydromorphone Compared to Morphine for Postoperative Analgesia: A Systematic Review and Meta-analysis: CONCLUSIONS: There was no significant statistical difference in postoperative analgesic effect between hydromorphone and morphine, as well as side effects, including severe sedation, nausea, and vo...; Wangyuan Zou. Pain physician. 2024-12-02 00:00:00
Long-term reoperation after decompression with versus without fusion among patients with degenerative lumbar spinal stenosis: a systematic review and meta-analysis: CONCLUSION: In lumbar spinal stenosis patients without spondylolisthesis, the addition of fusion after decompression showed limited benefits in terms of reoperation rates, ODI, and leg pain.; Chung Liang Chai. The spine journal : official journal of the North American Spine Society. 2024-11-30 00:00:00
Effect of Industry Funding on Outcome Reporting in Cervical Disc Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials: CONCLUSION: Cervical disc arthroplasty appears to be equivalent to ACDF in reducing postoperative pain and disability, while also potentially decreasing the risk for subsequent surgical interventio...; Ryan D Sauber. The spine journal : official journal of the North American Spine Society. 2024-11-29 00:00:00
Correction to 'Systematic review and co-ordinate based meta-analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensiti...: No abstract; . European journal of pain (London, England). 2024-11-15 00:00:00
The Impact of Disc Height on Outcomes Following Cervical Disc Replacement: A Systematic Review: CONCLUSIONS: "Disc height," especially as measured by DHC, may be an important intraoperative consideration when selecting implant size during CDR. Maintaining DHC <2 mm may optimize P...; Sheeraz Qureshi. Spine. 2024-11-11 00:00:00
Answer to the letter to the editor of Franz Jooji Onishi concerning "A systematic review of anterior lumbar interbody fusion (ALIF) versus posterior lumbar interbody fusion (PLIF), transforami...: No abstract; Matthew Scott-Young. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2024-11-05 00:00:00
Which spinal fixation technique achieves which degree of stability after thoracolumbar trauma? A systematic quantitative review: CONCLUSIONS: The stabilizing effect of surgical treatment depends on the type, severity, and location of injury, as well as the fixation strategy. There is an enormous range of surgical approaches...; Christian Liebsch. The spine journal : official journal of the North American Spine Society. 2024-11-04 00:00:00
Spinal hyperexcitability in patients with chronic musculoskeletal pain or headache as evidenced by alterations in the nociceptive withdrawal reflex: a systematic review and meta-analysis: The nociceptive withdrawal reflex (NWR) is a spinal withdrawal reflex induced by painful stimulation. It is a measure of spinal hyperexcitability, which is believed to contribute to chronic musculo...; Jessica Van Oosterwijck. Pain. 2024-10-29 00:00:00
Incidence of and risk factors for lumbar disc herniation with radiculopathy in adults: a systematic review: CONCLUSIONS: Incidence of LDH varies in different populations and according to case definition. Risk factors include individual, behavioural, and work-related variables. Our findings support the ne...; J David Cassidy. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2024-10-25 00:00:00
Performance of Artificial Intelligence in Diagnosing Lumbar Spinal Stenosis: A Systematic Review and Meta-analysis: CONCLUSIONS: AI is highly valuable for diagnosing LSS. However, further external validation is necessary to enhance the analysis of different stenosis categories and improve the diagnostic accuracy...; Zixiang Wu. Spine. 2024-10-25 00:00:00
The role of neutrophils in pain: systematic review and meta-analysis of animal studies: The peripheral inflammatory response is an attractive therapeutic target for pain treatment. Neutrophils are the first circulating inflammatory cells recruited to sites of injury, but their contrib...; Enrique J Cobos. Pain. 2024-10-25 00:00:00
Lived and care experiences of young people with chronic musculoskeletal pain and mental health conditions. A systematic review with qualitative evidence synthesis: Chronic musculoskeletal pain (CMP) and coexisting mental health conditions impact young people; however, little is known about their lived and care experiences. In a prospectively registered system...; Andrew M Briggs. Pain. 2024-10-24 00:00:00
Low-value interventions to deimplement: A secondary analysis of a systematic review of low back pain clinical practice guidelines: CONCLUSIONS: Clinicians managing patients with chronic LBP should consider deimplementing these low-value interventions (traction, TENS, TUS, and SSRI).; Thiru M Annaswamy. PM & R : the journal of injury, function, and rehabilitation. 2024-10-24 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. Reviews from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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