Hip Osteoarthritis

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Hip Osteoarthritis
Epidemiology ~4% symptomatic OA, ~20% radiographic OA, in age >50.
Tests Diagnostic intra-articular hip joint local anaesthetic injection


Epidemiology

A US study of mostly Caucasian people aged over 50, the prevalence of radiographic hip OA was 19.6%, and the prevalence of symptomatic disease was 4.2%, with the prevalence increasing with higher age. The authors found a male predominance of symptomatic OA, especially in older individuals, unlike other studies which have tended to find a female predominance. There is generally a male predominance of radiographic OA.[1] A Japanese study found the prevalence of radiographic hip osteoarthritis to be 18.2% in men and 14.3% in women[2]

Aetiopathogenesis

There are several structures around the hip that are richly innervated by sensory nerve fibres. These include the periosteum, subchondral bone, synovium, and surrounding soft tissues. In the presence of Central Sensitisation there may be an additional central physiological process. Hip osteoarthritis can also lead to changes in gait which can lead to pain in the knees and lumbar spine.[3]

Higher bone density can drive knee osteoarthritis but not hip osteoarthritis

Clinical Features

History

The pain is often poorly localised. Patients can have pain over quite a large area including the front of the thighs, groin, lateral thighs, buttocks, and the posterior upper thighs. Patients with Central Sensitisation can have unusual distributions of pain at a surprising distance from the hip such as below the knee.

There is no clear association between pain levels and radiographic severity of hip osteoarthritis. Up to 40% of patients with hip osteoarthritis have no pain. Patients with higher pain levels showed differences in sensitisation as measured by quantitative sensory testing.[4]

Examination

Main article: Hip Examination


Imaging

Plain radiographs can demonstrate joint space narrowing, osteophytes, subchondral sclerosis, and subchondral cysts. They may also show alternative causes for pain such as pelvic bone tumours. Plain radiographs are cheap, however because most patients with radiographic OA have asymptomatic disease, there is a risk of incorrectly attributing the pain to osteoarthritis, and subsequently having incorrect treatment. Therefore it is as important as ever to consider the pre-test probability, and consider other diagnoses.

Diagnosis

A commonly performed procedure in Musculoskeletal Medicine in New Zealand is the diagnostic intra-articular hip joint injection. Under either ultrasound or fluoroscopic guidance, local anaesthetic is infiltrated into the hip joint. An appreciable reduction in pain post-procedure is consistent with nociception arising from the hip joint.

Differential Diagnosis

Hip Pain Differential Diagnosis

Prognosis

  • A minority have clear cut clinical and radiological recovery, especially with marked osteophytosis and concentric disease
  • Superolateral migration of the femoral head is correlated with more rapid osteoarthritis progression, also with atrophic bone response

Treatment

Total hip joint replacement is usually effective for reducing pain. However 10% of patients have chronic postsurgical pain, and preoperative central sensitisation has been thought to be a risk factor for this.[4]

Resources

References

  1. โ†‘ Kim et al.. Prevalence of radiographic and symptomatic hip osteoarthritis in an urban United States community: the Framingham osteoarthritis study. Arthritis & rheumatology (Hoboken, N.J.) 2014. 66:3013-7. PMID: 25103598. DOI. Full Text.
  2. โ†‘ Iidaka et al.. Prevalence of radiographic hip osteoarthritis and its association with hip pain in Japanese men and women: the ROAD study. Osteoarthritis and cartilage 2016. 24:117-23. PMID: 26241774. DOI.
  3. โ†‘ Metcalfe et al.. Does This Patient Have Hip Osteoarthritis?: The Rational Clinical Examination Systematic Review. JAMA 2019. 322:2323-2333. PMID: 31846019. DOI. Full Text.
  4. โ†‘ 4.0 4.1 Hattori T, Shimo K, Niwa Y, Tokiwa Y, Matsubara T. Association of Chronic Pain with Radiologic Severity and Central Sensitization in Hip Osteoarthritis Patients. J Pain Res. 2021;14:1153-1160 DOI

Literature Review