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Myotomes
A myotome is the group of muscles innervated by a single spinal nerve. Many muscles are innervated by more than one spinal nerve root, and therefore consist of multiple myotomes, however some muscles commonly have dominant supply by a single nerve root. Understanding the myotomes is integral for performing an accurate motor system examination. In Musculoskeletal Medicine the concept is typically used in localising nerve root and peripheral nerve lesions. - Read More
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Differential Effects of Repetitive Transcranial Magnetic Stimulation on Mood and Pain Symptoms in People With Chronic Pain and Major Depressive Disorders—A Review
Ciampi de Andrade et al. European Journal of Pain. July 2025
ABSTRACT - Evidence shows rTMS has target- and symptom-specific effects: Motor cortex stimulation improves pain without reliably affecting mood, while dorsolateral prefrontal cortex stimulation alleviates depressive symptoms but inconsistently influences pain. These outcomes suggest that symptom improvement with rTMS is not global over different symptom clusters, but rather different for specific syndromes and the respective neural networks engaged by therapy. Personalised treatment strategies guided by pre-treatment connectivity profiles and symptom clusters, already in use for psychiatric disorders, could enhance outcomes in chronic pain management. However, limitations include small sample sizes, low session numbers and potential floor effects in studies involving non-depressed fibromyalgia patients.
“I will respect the hard-won scientific gains of those physicians in whose steps I walk, and gladly share such knowledge as is mine with those who are to follow.”
— The Hippocratic Oath: Modern Version, Lasagna 1964