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Lidocaine: Difference between revisions
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{{drug | |||
|image=1920px-Lidocaine.png | |||
|name= | |||
|other names= | |||
|dose= | |||
|maxdose=<ul><li>4.5 mg/kg with plain lidocaine</li><li>7 mg/kg with adrenaline</li><small>Note: Intercostal block safe dose is 10 times less.{{#pmid:24660158|golzari}}</small> | |||
|onset=2-5 minutes. | |||
|duration=<ul><li>Tissue infiltration: 75-90 mins, or 120-180 mins with adrenaline</li><li>Nerve blocks: 2-3 hours, or 3-5 hours with adrenaline.</li></ul> | |||
|class=Amino amide local anaesthetic | |||
|metabolism= | |||
|half life= | |||
|indications= | |||
|antagonists= | |||
|contraindications= | |||
|side effects= | |||
|interactions= | |||
|chemical structure= | |||
|drugbank ID= | |||
}} | |||
Lidocaine was the first clinically used amide local anesthetic in 1948. It is widely used because of its potency; rapid onset; tissue penetration; and effectiveness in infiltration, peripheral nerve block, and both epidural and spinal blocks. In peripheral nerve blockage 1-1.5% is sufficient to produce a motor blockade, while for epidural and spinal blocks higher strengths are used. | |||
==Chemical Structure== | |||
[[File:1920px-Lidocaine.png|400px]] | |||
==Lidocaine Cream== | ==Lidocaine Cream== | ||
Lidocaine cream is not readily available in New Zealand and is not subsidised. It has to be ordered over the internet. | Lidocaine cream is not readily available in New Zealand and is not subsidised. It has to be ordered over the internet. | ||
Revision as of 19:23, 4 May 2021
This article is a stub.
| Lidocaine | |
|---|---|
| |
| Drug class | Amino amide local anaesthetic |
| Maximum dose |
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| Onset of action | 2-5 minutes. |
| Duration of action |
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Lidocaine was the first clinically used amide local anesthetic in 1948. It is widely used because of its potency; rapid onset; tissue penetration; and effectiveness in infiltration, peripheral nerve block, and both epidural and spinal blocks. In peripheral nerve blockage 1-1.5% is sufficient to produce a motor blockade, while for epidural and spinal blocks higher strengths are used.
Chemical Structure
Lidocaine Cream
Lidocaine cream is not readily available in New Zealand and is not subsidised. It has to be ordered over the internet.
- Haim International for 10.56% lidocaine cream, apply twice daily
- 4% Lidocaine patches can be purchased from ebay, brand name is Salonpas. They last for 8 hours.
See Also
Analgesics | |||||||||||||
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| Opioids |
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| Paracetamol-type | |||||||||||||
| NSAIDs |
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| Cannabinoids | |||||||||||||
| Ion channel modulators |
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| Muscle Relaxants | |||||||||||||
| Others | |||||||||||||
